Protein Alignment NAAT1 and Slc6a2

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_033235.3
• Gene: Slc6a2 / 20538
• MGIID: 1270850
• Length: 617
• Species: Mus musculus
• Alignment Length: 606
• Identity: 218/606 - (35%)
• Similarity: 334/606 - (55%)
• Gaps: 46/606 - (7%)

  Fly    18 NGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYII 82
            ||.....:::.:||:    .|..||..::||:|.:..:|.|.||||||:..|:||||||||||.:
Mouse    40 NGVQCLLASQDSDAQ----PRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTL 100

  Fly    83 VLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFV 147
            .|.:.|.|::|:|:.:||:..:|...:|.:.|.|.||||......:.:..||:.::|.:|||||.
Mouse   101 FLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFA 165

  Fly   148 SFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETE----KLQSS 206
            ||...|||:.|...|.  ||             |...|.|.|       |..|.|:    |...:
Mouse   166 SFTLNLPWTNCGHSWNSPNC-------------TDPKLLNAS-------VLGDHTKYSKYKFTPA 210

  Fly   207 SELYFLNVV-IKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVL 270
            :|.|...|: :.|...|.| :|.|.|:|.|.|.|..||::..:.:|||:|||..:..|..||.||
Mouse   211 AEFYERGVLHLHESSGIHD-IGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVL 274

  Fly   271 FVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGI 335
            ||||:..|||.||.:||..:|...:..|...|||.:|..|.||||..|.|.:|.|||||:||:..
Mouse   275 FVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNC 339

  Fly   336 YRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQ 400
            ||||::.:|::.:||.:.|..||:|||.:||..:: ||.||...|.||.||.||:|||.... ..
Mouse   340 YRDALLTSTINCVTSFISGFAIFSILGYMAHEHKV-NIEDVATEGAGLVFILYPEAISTLSG-ST 402

  Fly   401 LFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKVALT--TSVCGFLMGLVYVTPGGQW 463
            .::||||.||..||:.|.:.....::|.:.|.|:..|..:...|  .::..||:.|..:|.||.:
Mouse   403 FWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLALFCITKGGIY 467

  Fly   464 ILTLVD-FYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMII 527
            :|||:| |..||.::|.: :.|..|:.|.||:..|.:||:.|...:..||||:||.|.:|..::.
Mouse   468 VLTLLDTFAAGTSILFAV-LMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLF 531

  Fly   528 IFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLW-YISRHPQGTYWKSLKASLKP 591
            :.:.|::..:|:.|.:..:|..||..||.:........|.:.:: ::|  .:|:.|:.:...:.|
Mouse   532 VVVVSIINFKPLTYDDYTYPPWANWVGWGIALSSMILVPAYVIYKFLS--IRGSLWERVAYGITP 594

  Fly   592 -SDRWGPANPEIR----REWV 607
             ::....|..::|    |.|:
Mouse   595 ENEHHLVAQRDVRQFQLRHWL 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	196/502 (39%)
Slc6a2	NP_033235.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SLC5-6-like_sbd	56..615	CDD:382020	213/584 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820