Protein Alignment NAAT1 and dat-1

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_499043.1
• Gene: dat-1 / 176304
• WormBaseID: WBGene00000934
• Length: 615
• Species: Caenorhabditis elegans
• Alignment Length: 576
• Identity: 190/576 - (32%)
• Similarity: 311/576 - (53%)
• Gaps: 36/576 - (6%)

  Fly    12 SSNGSGNGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAF 76
            :|||..|..........|:.:.|..|:  |...|:||:|.:..:|.|||:||||:..::||||.|
 Worm    16 TSNGMQNATLPIDGPVNTEPKDPAREQ--WSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVF 78

  Fly    77 LIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIISYYSSLLAL 140
            ||||.|::.|.|.|::|:|:.:||:..:|.:..|. :.|.|.|:||........:..:|:.:||.
 Worm    79 LIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAW 143

  Fly   141 TLYYLFVSFQSELPWSYCRDEWTNCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQS 205
            .|:||:.||...|||:.|.:.:.:.....|....|    |.::...:.:::|       .||:.:
 Worm   144 GLHYLYTSFSFNLPWASCNNSYNSPACYEPHWSED----GTAMCRSANQSVS-------AEKISA 197

  Fly   206 SSELY---FLNV---------VIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKA 258
            :.|.:   ||.:         ||:...|:    |:..|.:.|:|||.:::.:..:.:|:.:|||.
 Worm   198 AEEYFYKGFLGLHEANAPNSHVIRSVTDL----GNVRWDIALSLFVVYLICYFSMWKGIHTSGKV 258

  Fly   259 AYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPII 323
            .:|.||||||||.:|.||.|||.|.::||.::|.|.:..|..|:||::|..|.||||..|.|.::
 Worm   259 VWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLM 323

  Fly   324 MFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISY 388
            .::|||.|.:.:|.||:..:.::..||.|.|..||::||.::.. ..:.|..|.:.|.||.|:.|
 Worm   324 AYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYMSCK-SGKPIEAVAQEGPGLVFVVY 387

  Fly   389 PDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKVALTTSVCGFLM- 452
            |:|:|.....| .:|||||.||..||:.|.......|:|.:.|:|...|..:......:..|.|
 Worm   388 PEALSTMPYAP-FWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFPILKKNREVFVGCLFAFYMV 451

  Fly   453 -GLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVC 516
             |:...|.||..|:..:..||.|:.:.|....|...|.::|||:.|..|::.|...|...||:.|
 Worm   452 IGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKFC 516

  Fly   517 WSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQF-PLWGLW 571
            ||...|.:::.:...:.:..:.:.|.:..:|.|||:.| ::||:..|.| ||.|::
 Worm   517 WSCAAPFILLSMITSNFINYQALTYQDYTYPTAANVIG-IIFALSGASFIPLVGIY 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	170/507 (34%)
dat-1	NP_499043.1	SLC6sbd_SERT-like_u1	40..591	CDD:271405	184/552 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820