Protein Alignment NAAT1 and DAT

DIOPT Version :10

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_061499264.1
• Gene: DAT / 1269812
• VectorBaseID: AGAMI1_006978
• Length: 678
• Species: Anopheles gambiae
• Alignment Length: 577
• Identity: 206/577 - (35%)
• Similarity: 327/577 - (56%)
• Gaps: 35/577 - (6%)

  Fly     5 GVQPSNGSSNGSGNGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAY 69
            |:.|.||:..|.|.|     ..|..|.|    ||..|...::||:|.|..:|.|.||||||:..|
Mosquito    71 GLLPRNGAGGGGGGG-----GGELDDGE----ERETWSGKVDFLLSVIGFAVDLANVWRFPYLCY 126

  Fly    70 ENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWS-VVPGFVGVGYGQAFGTICIISY 133
            :||||||||||.|:|.:.|.|::|:|:.:|||..:|.:..|. :||.|.|:||........:..|
Mosquito   127 KNGGGAFLIPYGIMLVVGGIPLFYMELALGQFNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFY 191

  Fly   134 YSSLLALTLYYLFVSFQSELPWSYCRDEWTNCVNSRPQEYVDNLLTGVSLANES---ARNLSGIV 195
            |:.::|.:|.:.|.||...|||::|.:.| |.|..:|..|:::  |..::.|.:   |.|::|.|
Mosquito   192 YNVIIAWSLRFFFASFTDSLPWTHCSNAW-NTVECKPFGYINS--TAATVVNRTGVLAANVTGTV 253

  Fly   196 ANDETEKLQSSSELYFLNVVIKEKLDISDGV---GDPDWKLTLALFVAWVVIFLVIMRGVKSSGK 257
            :.....|..|::..||...::  :||.|:|:   |...|.:.|.|...:::.:..:.:|:.:|||
Mosquito   254 STINDTKFASAASEYFNRYIL--ELDKSEGIHDLGAIKWDMALCLLAVYLICYFSLWKGISTSGK 316

  Fly   258 AAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPI 322
            ..:|.|||||.||.:||:|.:||.|:.:|||::|.|.:..:.|..||.:|..|.||||..|.|.:
Mosquito   317 VVWFTALFPYAVLLILLVRGITLPGSAEGILYYLRPNFDVIYNAEVWVDAATQVFFSLGPGFGVL 381

  Fly   323 IMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFIS 387
            :.:||||::.:.:|:||::.:.:::.||.:.|..||::||.:|| ...::|:||...|.||.|:.
Mosquito   382 LAYASYNKYHNNVYKDALLTSLINSATSFIAGFVIFSVLGYMAH-ASGQSIQDVATEGPGLVFVV 445

  Fly   388 YPDAISKFQAVPQ--LFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWK-----VALTT 445
            ||.||:   .:|.  .::::||.||..||:.|.......|:|.:.|:|.  |..:     ||:..
Mosquito   446 YPAAIA---TMPGSIFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFP--KIGRNREIFVAVLF 505

  Fly   446 SVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVS 510
            |:. |::||...|.||.:...|:|.|...|.:.|...||...:.|:||.:.||:||:.|......
Mosquito   506 SLY-FVVGLASCTQGGFYFFQLLDRYAAGYSILIAVFFEAIAVSWIYGTERFCNDIKDMIGFAPG 569

  Fly   511 LYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPL 567
            :||||||.|..|:.::.|.||.::..||:.|.:..:|..||:.||.:........||
Mosquito   570 IYWRVCWKFVAPLFLLFIIIYGLIGHEPLSYEDYVYPSWANVLGWCIAGSSMIMIPL 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	184/506 (36%)
DAT	XP_061499264.1	None