Protein Alignment NAAT1 and Slc6a5

DIOPT Version :10

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_006540608.1
• Gene: Slc6a5 / 104245
• MGIID: 105090
• Length: 831
• Species: Mus musculus
• Alignment Length: 628
• Identity: 242/628 - (38%)
• Similarity: 361/628 - (57%)
• Gaps: 42/628 - (6%)

  Fly    21 TNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLF 85
            |.....|:.|..|   .|.||.:.|:|::|.:..:||||||||||:.|::||||||||||:::|.
Mouse   211 TTIPEDEQGDENK---ARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLA 272

  Fly    86 LIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQ 150
            |.|.|:::||:.:|||.|||.|.:|..:|...|.|......::.|..||:.::..||:|||.||.
Mouse   273 LAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFV 337

  Fly   151 SELPWSYCRDEWT--NCVNSRPQEYVDNLLTG----VSLANE-----SARNLSGIVANDETEK-L 203
            |.|||..|.:.|.  .| ..:.:..:|:.:.|    :.:.|.     :..||:.:....:|.| .
Mouse   338 SVLPWGSCNNPWNTPEC-KDKTKLLLDSCVIGDHPKIQIKNSTFCMTAYPNLTMVNFTSQTNKTF 401

  Fly   204 QSSSELYFLNVVIKEKLDISDGV---GDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALF 265
            .|.||.||...|:|    ||.|:   |:..|.|...||:|||:::..:.:|:|||||..||.|.|
Mouse   402 VSGSEEYFKYFVLK----ISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATF 462

  Fly   266 PYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNR 330
            |||||.:||||.|||.||..||.:|:.|:|.:|.:.||||:|..|.||||:...|.:|..:|||:
Mouse   463 PYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNK 527

  Fly   331 FDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKF 395
            |.:..|||.:|||..::.||:..|..||:::|.:|:..:: ||.:|...|.|:||:.||:|:::.
Mouse   528 FHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKV-NIENVADQGPGIAFVVYPEALTRL 591

  Fly   396 QAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKV-----ALTTSVCGFLMGLV 455
            ...| .::::||.||..||:.::.|...||||.|.|:|.  ||.:.     .|...:|.|:||..
Mouse   592 PLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFP--KYLRTHKPVFTLGCCICFFIMGFP 653

  Fly   456 YVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFF 520
            .:|.||.::..|||.|..:|.:.|:|||||.||.:|||||.||:|||.|...:.:::|:|||:|.
Mouse   654 MITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFKPNIFWKVCWAFV 718

  Fly   521 TPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRH-PQGTYWKS 584
            ||.::..|..:|....||:.|....:|..:.:.|||:.|......|:  ::.|..: ..|.:.:.
Mouse   719 TPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPI--MFVIKMYLAPGRFIER 781

  Fly   585 LKASLKPSDRWGPANPEIRREWVIFKNQKAAQRATQKDTSKLG 627
            ||....|...|||...:.|.|  .:||.     .....||.||
Mouse   782 LKLVCSPQPDWGPFLAQHRGE--RYKNM-----IDPLGTSSLG 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	211/512 (41%)
Slc6a5	XP_006540608.1	SLC6sbd_GlyT2	225..821	CDD:271389	238/611 (39%)