Protein Alignment NAAT1 and Slc6a8

DIOPT Version :10

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_598748.1
• Gene: Slc6a8 / 102857
• MGIID: 2147834
• Length: 640
• Species: Mus musculus
• Alignment Length: 614
• Identity: 219/614 - (35%)
• Similarity: 326/614 - (53%)
• Gaps: 69/614 - (11%)

  Fly     8 PSNGSSNGSGNGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENG 72
            |....:.|.|.....|..     .......|..|...::|:|||:..:||||||||||:..|:||
Mouse    27 PDGAPAKGDGPAGLGAPG-----GRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNG 86

  Fly    73 GGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTICIISYYSSL 137
            ||.|||||:::..:.|.|:::||:.:|||...|::.:|::.|.|.|:||..........:||..:
Mouse    87 GGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMV 151

  Fly   138 LALTLYYLFVSFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDET 200
            ||...|||..||.:.|||:.|...|.  :||.....|         ..||.|..||:    .|:.
Mouse   152 LAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHE---------DCANASLANLT----CDQL 203

  Fly   201 EKLQSSSELYFLNVVIKEKLDISDGVGDP---DWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFL 262
            ...:|....::.|.|::    :|.|:..|   :|::||.|...||:::..:.:||||:||..||.
Mouse   204 ADRRSPVIEFWENKVLR----LSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFT 264

  Fly   263 ALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFAS 327
            |.||||||.|||:|.|.|.||.|||:::|:|.|.:|.:|.||.:|..|.|||.|:|.|.:....|
Mouse   265 ATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGS 329

  Fly   328 YNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAI 392
            ||||::..|:||:|:..:::.||...|..:|:|||.:|.. |..:|..|..||.|||||:||.|:
Mouse   330 YNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATE-QGVHISKVAESGPGLAFIAYPRAV 393

  Fly   393 SKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWK------VALTTSVCGFL 451
            :.....| |::.||||||.:||:.|........:|.:.|......|::      |||..::| |:
Mouse   394 TLMPVAP-LWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALC-FV 456

  Fly   452 MGLVYVT-----PGGQWILTLVDFY--GGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRV 509
            :.|..||     .||.::..|.|:|  .||.::: .|.:|...:.||||...|.|||..|...|.
Mouse   457 IDLSMVTDVSGGKGGMYVFQLFDYYSASGTTLLW-QAFWECVVVAWVYGADRFMDDIACMIGYRP 520

  Fly   510 SLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELY-FPEAANIAGW-----------------L 556
            ..:.:.|||||||::.:.|||:::|..||:.|:..| :|......||                 |
Mouse   521 CPWMKWCWSFFTPLVCMGIFIFNIVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCL 585

  Fly   557 LFAIG--AAQF-----PLWGLWYISRHPQ 578
            |.|.|  |.::     |:|||.::....|
Mouse   586 LRAKGTMAERWQHLTQPIWGLHHLEYRAQ 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	196/510 (38%)
Slc6a8	NP_598748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		219/614 (36%)
		SLC6sbd_CT1	52..626	CDD:271397	215/584 (37%)