Protein Alignment NAAT1 and slc6a6

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 609
• Identity: 220/609 - (36%)
• Similarity: 334/609 - (54%)
• Gaps: 57/609 - (9%)

  Fly     6 VQPSNGSSNGSGNGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYE 70
            ::||.|.|.|:       ...::.|.:.|  :|..|.:.::|::|.....:|||||||||:..|:
 Frog    18 LKPSPGKSPGT-------RPEDEADGKPP--QREKWASKIDFVLSVAGGFIGLGNVWRFPYLCYK 73

  Fly    71 NGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIW-SVVPGFVGVGYGQAFGTICIIS-- 132
            ||||||||||.|.||..|.|:::||:::|||||:|.:..| .:.|.|.|:||    .:|.|:|
 Frog    74 NGGGAFLIPYFIFLFGGGLPVFFLEVVLGQFTSEGGITCWEKICPVFTGIGY----ASIVIVSLL 134

  Fly   133 --YYSSLLALTLYYLFVSFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANESARNLSG 193
              ||..:||..:||||.|||.:|||:.|...|.  :||.   ..:..|....:|:   ::.|.:.
 Frog   135 NVYYIVILAWGVYYLFQSFQGQLPWALCHQPWNTESCVE---DTFRKNWTMWMSM---NSTNFTS 193

  Fly   194 IVANDETEKLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKA 258
            .|......|:.|.|:..             |.||...|.|.|.|.:.||:.|..|.:||:|:||.
 Frog   194 PVTEFWEHKVLSLSKGI-------------DDVGVLKWDLALCLLLTWVICFFCIWKGVRSTGKV 245

  Fly   259 AYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPII 323
            .||.|.||:::|.|||||.|||.||.:||.|:|.|....|.:|.||.:|..|.|||.|:..|.:.
 Frog   246 VYFTATFPFIMLLVLLIRGVTLPGAAEGIKFYLYPDITRLADPQVWIDAGTQIFFSYAICLGAMT 310

  Fly   324 MFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISY 388
            ...|||::.:..|||.|::..|::.||.:.|..||::||.:|....:: |.||..||.|||||:|
 Frog   311 SLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGFAIFSVLGFMAQEQGVD-IADVAESGPGLAFIAY 374

  Fly   389 PDAISKFQAVPQLFSVLFFFMLFVLGIGS-IVALQSTIVTIICDQF-----KGWKYWKVALTTSV 447
            |.|:| ...:|..:::|||.||.:||:.| .|.::..|.::: |.:     ||  |.:......|
 Frog   375 PKAVS-MMPLPSFWAILFFIMLLLLGLDSQFVEVEGQITSLV-DLYPSFLRKG--YRREIFIAVV 435

  Fly   448 C--GFLMGLVYVTPGGQWILTLVDFYGGTYVVFI-LAIFELAGIVWVYGLQNFCDDIEFMCNRRV 509
            |  .:|:||..||.||.::..|.|:|..:.|..: :|.||...:.||||...|.|:||.|...:.
 Frog   436 CFLSYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECVAVAWVYGADKFYDNIEDMIGYKP 500

  Fly   510 SLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELY-FPEAANIAGWLLFAIGAAQFPLWGLWYI 573
            ..:.:..|:..||::.:..||:|:....|:.|::.| :|:.|...||:|........||..:::|
 Frog   501 GPWMKWSWTVITPLLCVACFIFSLAKYTPLTYNKYYVYPDWAIGLGWVLALSSMICIPLVVVFHI 565

  Fly   574 SRHPQGTYWKSLKASLKPSD--RW 595
            .| ..|:..:.:||...|.:  ||
 Frog   566 VR-SDGSLIERIKAVTAPREVNRW 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	193/508 (38%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	210/569 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920