Protein Alignment NAAT1 and slc6a4

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017946918.1
• Gene: slc6a4 / 100493853
• XenbaseID: XB-GENE-22062972
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 627
• Identity: 215/627 - (34%)
• Similarity: 326/627 - (51%)
• Gaps: 79/627 - (12%)

  Fly     8 PSNGSSNGSGNGAT------NAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPF 66
            |.||..||...|:|      .|...|....:....||..|...::||:|.|..:|.||||||||:
 Frog    77 PCNGMRNGGDEGSTPTLTVLPACRAEIQHLQTEIGERETWSKKIDFLLSVIGYAVDLGNVWRFPY 141

  Fly    67 TAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIW-SVVPGFVGVGYGQAFGTICI 130
            ..|:||||||||||:|:....|.|::|:|:.|||:...|.:.|| .:.|.|.|:||     .||:
 Frog   142 VCYQNGGGAFLIPYVIMAVFGGIPLFYMELAMGQYHRNGCISIWRKICPLFKGIGY-----AICM 201

  Fly   131 IS-----YYSSLLALTLYYLFVSFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANESA 188
            |:     ||::::|..||||..||:|||||:.|.:||.  ||.|     |..|  :.|..:|.|.
 Frog   202 IALYVAFYYNTIMAWALYYLIFSFRSELPWTSCLNEWNTGNCTN-----YFQN--SSVGWSNSSI 259

  Fly   189 RNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDG---VGDPDWKLTLALFVAWVVIFLVIMR 250
                            |.:|.::..:|:  ::..|.|   :|...|:|||.|.:.:.|::..|.:
 Frog   260 ----------------SPAEEFYTRLVL--QIHKSKGLHDLGGISWQLTLCLLLIFTVVYFSIWK 306

  Fly   251 GVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSL 315
            |||:|||..:..|.|||:||.:||||..||.||..|:||:|:|.|.:||...||.:|..|.||||
 Frog   307 GVKTSGKVVWVTATFPYIVLALLLIRGATLPGAWRGVLFYLQPDWEKLLTTAVWVDAAAQIFFSL 371

  Fly   316 AVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLA--HNLQIENI-RDVV 377
            ..|.|.::.|||||:|.:..|:||:|.:|::.:||.:.|:.||.:||.:|  .||.:..: :|
 Frog   372 GPGFGVLLAFASYNKFHNNCYQDALITSTVNCMTSFMSGLVIFTVLGYMAEMRNLDVSEVAKD-- 434

  Fly   378 RSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWK-- 440
             :|..|.||:|.:||:...| ...|:::||.||..||:.|..|....::|.:.|:|.  ..|.
 Frog   435 -TGPSLLFITYAEAIANMPA-STFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFP--HIWGKR 495

  Fly   441 ----VALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDI 501
                |.|..||| ||..|..:|.||.:::.|.:.|.....|..:...|...:.|.||:..||.|:
 Frog   496 RELFVFLLISVC-FLGALSTLTFGGAYMVKLFEEYATGPAVLTVVFLEAIAVSWFYGINQFCRDV 559

  Fly   502 EFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQF- 565
            ..|.......:|::||....|:.::.|....|.:...::.....:|....:.|   :.||.:.|
 Frog   560 REMLGFSPGWFWKICWVAICPLFLLFIICSFMSSPPDLRLFNYQYPSWTVVLG---YCIGTSSFI 621

  Fly   566 --PLWGLWYISRHPQGTYWKSLKASLKPSDRWGPANPEIRRE 605
              |.:.::.::..|.....:.||:          ..||:.||
 Frog   622 CVPAYMVYLLTSTPGSIKERFLKS----------ITPEVSRE 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	190/512 (37%)
slc6a4	XP_017946918.1	5HT_transport_N	48..91	CDD:367522	6/13 (46%)
		SLC5-6-like_sbd	113..649	CDD:382020	201/585 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010