Protein Alignment NAAT1 and slc6a8

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_002935539.1
• Gene: slc6a8 / 100489909
• XenbaseID: XB-GENE-986840
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 221/638 - (34%)
• Similarity: 341/638 - (53%)
• Gaps: 68/638 - (10%)

  Fly     2 ELKGVQPSNGSSNGSG---NGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWR 63
            |.||....||::..:.   ||:.........:.::...||..|.:.::|:|||:..:||||||||
 Frog    19 EKKGQLIPNGTAQETDLCRNGSAKGEIVFPPNCKEGIPERDTWTSQMDFIMSCVGFAVGLGNVWR 83

  Fly    64 FPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTI 128
            ||:..|:||||.||||||::..|.|.|:::||:.:|||...|::.:|::.|.|.|:|    |.::
 Frog    84 FPYLCYKNGGGVFLIPYILIAILGGIPIFFLEIALGQFMKAGSIAVWNIAPLFQGIG----FASV 144

  Fly   129 CII----SYYSSLLALTLYYLFVSFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANES 187
            .|:    :||..:|...:|||..||.:.||||:|.:.|.  :||:...||...|     ..||.:
 Frog   145 VIVFFCNTYYILILTWGVYYLVKSFSAVLPWSHCNNTWNSPDCVDIFRQEDCTN-----GTANST 204

  Fly   188 ARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDG---VGDPDWKLTLALFVAWVVIFLVIM 249
            ..||:   .|:..:|:...:|.:     .|:.|.:|.|   :|..:|:|.|.|...|::::..:.
 Frog   205 FGNLT---CNELADKVSPITEFW-----EKKVLRLSSGLDDIGSINWELLLCLIGCWLLVYFCVW 261

  Fly   250 RGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFS 314
            :||||:||..||.|.||||||.:||:|...|.||.:||:::|:|.|.:|....||.:|..|.|||
 Frog   262 KGVKSTGKIVYFTATFPYVVLLILLVRGAMLPGATEGIIYYLKPDWSKLGTAQVWIDAGTQIFFS 326

  Fly   315 LAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRS 379
            .|:|.|.:....|||||::..|:||.|:..:::.||...|..:|:|||.:| |.|..:|..|..|
 Frog   327 YAIGLGALTALGSYNRFNNDCYKDAFILAVINSGTSFFAGFVVFSILGFMA-NEQGVDISKVAES 390

  Fly   380 GTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKV--A 442
            |.|||||:||.|:|.....| |:|.||||||.:||:.|.......::|.|.|......|::.  .
 Frog   391 GPGLAFIAYPRAVSLMPVAP-LWSALFFFMLLLLGLDSQFVGVEGLITAILDLLPARYYFRFQRE 454

  Fly   443 LTTSVC---GFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIF-ELAGIVWVYGLQNFCDDIEF 503
            :..::|   .||:.|..:|.||.::..|.|:|..:.:..:...| :...:.||||...|.|||..
 Frog   455 IAVAICCAIMFLIDLSMLTEGGMYVFQLFDYYSASGMTLLWQTFWQCVVVAWVYGADRFMDDIAR 519

  Fly   504 MCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELY-FPEAANIAGW------------ 555
            |...|...:.:.||||.||.:.:.||:::::..:|:.|:..| :|......||
 Frog   520 MIGYRPFPWMKWCWSFVTPFVCMAIFLFNLINYKPLTYNNSYTYPWWGEAIGWGFALSSMLCVPV 584

  Fly   556 -LLFAIGAAQ-----------FPLWG---LWYISRHPQGTYWKSLKASLKPSD 593
             .|:.|..|:           .|:||   |.|::..|.   .|||......||
 Frog   585 TFLYKITCAKGSLRERWQHLTKPIWGAHHLEYMAPDPD---VKSLTTLTPVSD 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	192/507 (38%)
slc6a8	XP_002935539.1	SLC5-6-like_sbd	58..644	CDD:382020	213/599 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820