DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and si:ch211-132b12.3

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001076419.1	Gene:	si:ch211-132b12.3 / 100002232	ZFINID:	ZDB-GENE-050419-161	Length:	577	Species:	Danio rerio

Alignment Length:	579	Identity:	213/579 - (36%)
Similarity:	315/579 - (54%)	Gaps:	58/579 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 TAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMG 99
            |.||..||...|||::.....||:|||||||:..|.||||.|||||::.:...|.|::.||.:||
Zfish     8 TEERGFWGRKAEFLLAVAGNVVGVGNVWRFPYLCYRNGGGVFLIPYLVFVMTCGVPLFLLETVMG 72

  Fly   100 QFTSQGTVKIWSVV-PGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWT 163
            |||.:|.:..|.:: |...||||......:....|::.:||..|:||..||.|:|||:.|.:.|.
Zfish    73 QFTHEGGITCWHLLCPLAQGVGYAGQLIELYSCMYFTIILAWALFYLIFSFSSQLPWASCDNIWN 137

  Fly   164 --NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSS---ELYFLNVVIKEKLDIS 223
              ||||               ||       :|.:..:.|.::.|:|   |.:...|     |.:|
Zfish   138 TDNCVN---------------LA-------AGNLTFNRTTQINSTSAATEFWERRV-----LSLS 175

  Fly   224 DG---VGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARD 285
            .|   :|..:|::.|.|||.|::.:..|.:||||:||..||.|.||||:|.|||||.:||.||..
Zfish   176 GGIEEIGKINWEIALCLFVMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQ 240

  Fly   286 GILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTS 350
            |::|:|.|:...|.:|.||.||..|.|||.::.||.:|...|||::.:..|||:..:..|::.||
Zfish   241 GVVFYLYPEPAHLADPQVWMEAGTQVFFSYSLCSGILIALGSYNQYSNNCYRDSFWLCLLNSGTS 305

  Fly   351 LLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGI 415
            .:.|..:|::||.:|| :|...:.:|..||.|||||:||.|:: ....|||::|.||.|:.:||:
Zfish   306 FVAGFAVFSVLGFMAH-VQGVPVEEVAESGPGLAFIAYPQAVA-MMPFPQLWAVCFFIMIILLGL 368

  Fly   416 GSIVALQSTIVTIICDQF------KGWKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGT 474
            .|.......:||.:.|.|      .|.:...|.|....| |...|:.||.||.::..|.|.|...
Zfish   369 DSQFVAMECVVTSVTDLFPEVLRRAGRRELFVLLLCLTC-FFGQLIMVTEGGMYVFQLFDNYASN 432

  Fly   475 YVVFI-LAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEP 538
            ...|: |::||...|.|::|.:...|.|:.|...|.:.::.:||.:.||::.:..|:||||...|
Zfish   433 GACFLFLSVFESLTIGWIFGAEKMFDIIKDMTESRPNYWFMLCWKYLTPLVSLTSFVYSMVRYTP 497

  Fly   539 IKYSELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDRWG 596
            :.|:..| :|:.|::.||||........|.|.|..:.         :.|.|||  .|||
Zfish   498 LTYNRWYVYPDWAHVLGWLLALSSILLVPGWALGQMC---------TGKGSLK--QRWG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	188/508 (37%)
si:ch211-132b12.3	NP_001076419.1	SLC6sbd-TauT-like	11..550	CDD:271387	211/576 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820