Protein Alignment SK and kcnl-4

DIOPT Version :9

• Sequence 1: NP_001284887.1
• Gene: SK / 31456
• FlyBaseID: FBgn0029761
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: NP_001256594.1
• Gene: kcnl-4 / 183736
• WormBaseID: WBGene00008265
• Length: 485
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 151/525 - (28%)
• Similarity: 261/525 - (49%)
• Gaps: 63/525 - (12%)

  Fly   373 IAGIAADSLRINGGMRPFKQLRKPASTLSIPGSMKTPSIANREQISSGCNEEAAEALVGIHSDYP 437
            :|.:.|.::.::      ||.|....:.:.|||       :.:...||..|.|.::...::.  .
 Worm     1 MAAVRAGAVGLS------KQARFTMYSSTRPGS-------DWDSRDSGTGERARQSRPSVYG--K 50

  Fly   438 RYMEERALTGGNTSRKPSTNSAKHKPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENE 502
            ||  ..|::...|.||              |...|:.|.:.:.::.|..|::.:.|:|:.:::.|
 Worm    51 RY--GVAMSNAETVRK--------------RWKIRRRLSDLKVKLCDATLILAVGGLILAMLDVE 99

  Fly   503 LSSAGV---YTKASFYSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQR 564
            .::..:   :...|..|..|:|...::|:.||..::.||.::::::|  ::....:||:.:|.:|
 Worm   100 FTATRILESFVNTSDLSFILRTAAIITTIALLFFLLFYHFIDIKIQL--VETGTSNWRVGITSER 162

  Fly   565 ISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHS 629
            :....||:.||||.|||......|........:|.....:|..|.|:||||||.:::||.|:|||
 Worm   163 VLNTLLEVAICAICPIPETGVVAWPILSNIAERTRERVNIPISVLLTLPMFLRFFIVCRYMVLHS 227

  Fly   630 KLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERF------- 687
            ....|.::|:|.:||.|..:.|||||:.|...|..||.:..:..|.:.||.|.||||:
 Worm   228 SQHQDTATRTIASLNHIAVDFRFVLKSEMYERPLFVLSIASLMFWCVVSWMLTQCERYAYPSISG 292

  Fly   688 --HDEEHANLLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELT 750
              |..::      :|...|||.|:|:||:..|||||||:|:.|.|:|...::.|:|::||||.||
 Worm   293 FQHFADY------LWFEIITFFSIGYGDVQVNTYCGRGLAMLTAIVGTLFSSTLIALISRKLILT 351

  Fly   751 RAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTR----LVKRVNPGRVRTHQRKFLLAIYA 811
            ..||.|::.:.:..:|...|||||.||:.||......|    ...|.|..|:...||..|.::..
 Worm   352 TCEKRVNHIIAENNITNEHKNAAACVLQNTWRTVLRARDYQKSSSRRNQQRLAKMQRMLLCSVIT 416

  Fly   812 LRKVKMDQRKLMDNANTITDMAKTQNTVYEIISDMSSRQDAIEERLTNLEDKMQSIQEHMESLPD 876
            .||.:...|..|::.:...       |.....::...|...:.:|.:.|:.|:..:.|::|:|..
 Worm   417 FRKTRWKLRMQMEDEDDFF-------TARRAFNETEDRLQKVRQRQSQLDGKISMLFENVEALTQ 474

  Fly   877 -LLSR 880
             ::||
 Worm   475 AVMSR 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SK	NP_001284887.1	SK_channel	472..582	CDD:281522	29/112 (26%)
		Ion_trans_2	669..748	CDD:285168	33/87 (38%)
		CaMBD	762..834	CDD:280961	21/75 (28%)
kcnl-4	NP_001256594.1	SK_channel	69..180	CDD:367547	29/112 (26%)
		Ion_trans_2	261..349	CDD:369572	35/93 (38%)
		CaMBD	363..435	CDD:383459	21/71 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160750
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D907751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10153
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950