Protein Alignment SK and Kcnn4

DIOPT Version :9

• Sequence 1: NP_001284887.1
• Gene: SK / 31456
• FlyBaseID: FBgn0029761
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: NP_001156982.1
• Gene: Kcnn4 / 16534
• MGIID: 1277957
• Length: 425
• Species: Mus musculus
• Alignment Length: 435
• Identity: 179/435 - (41%)
• Similarity: 252/435 - (57%)
• Gaps: 47/435 - (10%)

  Fly   469 LGKRKALFEKRKRISDYALVMGMFGIIVMVIENE-LSSAGVYTKASFYSTALKTLISVSTVILLG 532
            |.:||.|.|:.||::.:|||:...||.:||:..| |...|  .|...|...:|.||::||..||.
Mouse    12 LRRRKRLLEQEKRVAGWALVLAGTGIGLMVLHAEMLWFLG--CKWVLYLLLVKCLITLSTAFLLC 74

  Fly   533 LIVAYHALEVQVRLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIP---------GEYYFQW 588
            |||.:||.|||  |||.||...|||:|:|.::::||.|||.:|.:||:|         ||
Mouse    75 LIVVFHAKEVQ--LFMTDNGLRDWRVALTRRQVAQILLELLVCGVHPVPLRSPHCALAGE----- 132

  Fly   589 TTKLANKNKTIGTEMVPY-------DVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRI 646
                       .|:..|:       :..|||.|.|||||:.|.:||.|.:..:||.|||||||::
Mouse   133 -----------ATDAQPWPGFLGEGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQV 186

  Fly   647 NFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHANLLNAMWLIAITFLSVGF 711
            .|...||.|..|...||.:||...:.||:..:|.|...||.......:|.:.:|||.||||::|:
Mouse   187 RFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLTDTLWLIPITFLTIGY 251

  Fly   712 GDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANV 776
            ||:||.|..|:.:.:.||:||..|||||||||:||||..:|||||||||||....|.:|.:||.:
Mouse   252 GDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIHYAKEMKESAARL 316

  Fly   777 LRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQNTVYE 841
            |:|.|:.|||||   |.:....|.||||.|.||:..|:|::..|||.:..|::.|::|....:.:
Mouse   317 LQEAWMYYKHTR---RKDSRAARRHQRKMLAAIHTFRQVRLKHRKLREQVNSMVDISKMHMILCD 378

  Fly   842 IISDMSSRQDAIEERLTNLEDKMQSIQEHMESLPDLLSRCLTQHQ 886
            :...:||...|:|:|:..|..|       :::|.:||...|.|.|
Mouse   379 LQLGLSSSHRALEKRIDGLAGK-------LDALTELLGTALQQQQ 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SK	NP_001284887.1	SK_channel	472..582	CDD:281522	52/119 (44%)
		Ion_trans_2	669..748	CDD:285168	36/78 (46%)
		CaMBD	762..834	CDD:280961	29/71 (41%)
Kcnn4	NP_001156982.1	SK_channel	15..121	CDD:367547	51/109 (47%)
		Ion_trans_2	<235..288	CDD:369572	30/52 (58%)
		Calmodulin-binding. /evidence=ECO:0000250	284..345		34/63 (54%)
		CaMBD	302..374	CDD:198121	30/74 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839449
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3684
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265878at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10153
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850