Protein Alignment SK and kcnn4

DIOPT Version :9

• Sequence 1: NP_001284887.1
• Gene: SK / 31456
• FlyBaseID: FBgn0029761
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_004916452.1
• Gene: kcnn4 / 101732300
• XenbaseID: XB-GENE-1013002
• Length: 474
• Species: Xenopus tropicalis
• Alignment Length: 433
• Identity: 186/433 - (42%)
• Similarity: 272/433 - (62%)
• Gaps: 24/433 - (5%)

  Fly   448 GNTSRKPSTNSA---KHK-------PNVGYR-LGKRKALFEKRKRISDYALVMGMFGIIVMVIEN 501
            |:...|..|..|   .||       ||...| ..:||.|.|.:|:||.:.:::.:.|||:||:..
 Frog    38 GDMQAKEPTEVAILNSHKVHIVRDDPNENLRKFKRRKGLVETKKKISAWTILVALLGIILMVVHT 102

  Fly   502 ELSSAGVYTKASF--YSTALKTLISVSTVILLGLIVAYHALEVQVRLFMIDNCADDWRIAMTWQR 564
            ||.   .|:|..:  |...:|..||:|||||:.||:|:|..|:|:  ||.||...|||||:..:.
 Frog   103 ELM---WYSKCEWFPYLFLVKCSISISTVILIILIIAFHLKEIQI--FMNDNSLQDWRIAINAKN 162

  Fly   565 ISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHS 629
            |..|.||:.:|||||.|  |..|...:..|.::.: ..:...|:.||:.||||:||:.|.:||:|
 Frog   163 IGWILLEVVVCAIHPFP--YVLQCVEEQGNNSEEL-EFLSEADIFLSILMFLRVYLLPRTVLLYS 224

  Fly   630 KLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHDEEHAN 694
            ::..|.|.||||:||:|.|..:||:|.||..|||.|||:..:|||:::||.|..|||.......:
 Frog   225 RVLGDTSYRSIGSLNKIKFQYKFVMKVLMNTCPGKVLLILSISLWVVSSWVLSVCERKKQVPTGD 289

  Fly   695 LLNAMWLIAITFLSVGFGDIVPNTYCGRGIAVSTGIMGAGCTALLVAVVSRKLELTRAEKHVHNF 759
            :.||:|||.||||::|:||:||||.||:.:.:|||:||.|||||:|||.::|||.||||||||.|
 Frog   290 MTNALWLIPITFLTIGYGDMVPNTVCGKLVCLSTGVMGVGCTALIVAVAAQKLEFTRAEKHVHTF 354

  Fly   760 MMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMD 824
            |||.:..|::|.||||||.|.||:::||   |:.:..:.|.|||..|.||:..|:.::..:.|.|
 Frog   355 MMDIRCMKQIKCAAANVLGEAWLLHRHT---KKGDKAQTRQHQRNLLRAIHVFRRSRISHKNLKD 416

  Fly   825 NANTITDMAKTQNTVYEIISDMSSRQDAIEERLTNLEDKMQSI 867
            ..|.:.|::|.|..:.::..:.||....:|:|:..|:.|:..|
 Frog   417 QMNAMVDISKMQMIMEDLDLNFSSSHRELEKRIDQLDKKLDDI 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SK	NP_001284887.1	SK_channel	472..582	CDD:281522	49/111 (44%)
		Ion_trans_2	669..748	CDD:285168	41/78 (53%)
		CaMBD	762..834	CDD:280961	27/71 (38%)
kcnn4	XP_004916452.1	SK_channel	73..180	CDD:367547	50/113 (44%)
		Ion_trans_2	266..343	CDD:369572	41/76 (54%)
		CaMBD	357..426	CDD:367232	27/71 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265878at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10153
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020