DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment XRCC1 and ATXRCC1

DIOPT Version :9

Sequence 1:	NP_572217.1	Gene:	XRCC1 / 31451	FlyBaseID:	FBgn0026751	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001077856.1	Gene:	ATXRCC1 / 844382	AraportID:	AT1G80420	Length:	353	Species:	Arabidopsis thaliana

Alignment Length:	392	Identity:	91/392 - (23%)
Similarity:	152/392 - (38%)	Gaps:	143/392 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 SSRHSLDKSISKEDK--PPAKEHNSSSREKSTAKEEKEQLRKEERSHSKEEKSRRKEKSKHDHRS 377
            |.:.:|...:|..|.  .|:|.|         .|:.|::      ..::|..||....:|.:| :
plant     2 SQKRNLPSWMSSRDPEITPSKSH---------CKKPKDE------GPTEEHNSRNAPSNKSEH-A 50

  Fly   378 SDTSNSKESSRPTAQKRHSSPTAVAVTPAKKQKIVDTAIQYRPLNQLLKGVVLVISGIQNPDRAD 442
            ..:||:.|.|:                                   |::|||.|:||..||:|:.
plant    51 EPSSNTTEFSK-----------------------------------LMEGVVFVLSGFVNPERST 80

  Fly   443 LRSKAVALGAKYKADWGSGCTHLICAFKNTPKYNQVK-GKGKIVTRSWIEKCYELKK------YL 500
            |||:|:.:||.|:.||.:|.|.|||||.||||:.||: ..|.|:::.||.:||..||      ||
plant    81 LRSQALTMGATYQPDWNAGSTLLICAFPNTPKFRQVETNGGTIISKEWITECYAQKKLVDIEQYL 145

  Fly   501 -----PWRRYA----------------------LDTNDIGQPES---DEELCDEATRP------- 528
                 |||:.:                      ..|...|.|.:   :...|:....|
plant   146 MHAGKPWRKSSSPQDANREKREHLSKKPEKQVEKKTETRGTPSTSSKNRSACNLVKEPFFVTEVK 210

  Fly   529 --RRDSSKDDVAMLED-------SKLTALADQNDVEMNPDALSGIDTEDELQRVAE--------- 575
              .||.....::.||.       .::..:|.:..:....||:..::.:.::..|.|
plant   211 KWARDDLSQTISWLESQEEKPEPGEIKRIAAEGVLTCLQDAIDSLEQKQDIGSVTELWSFVPRVV 275

  Fly   576 ------ENKTKK-----AKLRTTVKTKS-QDIYEV---------ST-------DEEDYLELKKKQ 612
                  |:.:||     :|.....:.|| :.|||.         ||       |.:..:|:.:::
plant   276 KELGKMESSSKKENSTASKEEVCKQAKSWKKIYEAELAKPGEDESTSRVACGYDSDMTVEMTEEE 340

  Fly   613 ID 614
            |:
plant   341 IE 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
XRCC1	NP_572217.1	XRCC1_N	1..144	CDD:280080
XRCC1	NP_572217.1	BRCT	420..494	CDD:278934	36/74 (49%)
ATXRCC1	NP_001077856.1	BRCT_XRCC1_rpt1	65..144	CDD:349357	39/78 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	84	1.000	Domainoid score	I2874
eggNOG	1	0.900	-	-		E1_KOG3226
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007184
OrthoInspector	1	1.000	-	-		oto3584
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11370
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.000