DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment XRCC1 and Xndc1

DIOPT Version :9

Sequence 1:	NP_572217.1	Gene:	XRCC1 / 31451	FlyBaseID:	FBgn0026751	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001316819.1	Gene:	Xndc1 / 102549471	RGDID:	7692537	Length:	407	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	91/352 - (25%)
Similarity:	144/352 - (40%)	Gaps:	56/352 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SSEDAVHVAANLLKENAGKKWRTKAPGEKSAYVVLEF--EEPQQITGIDIGNEHAAFIEVLVSRT 75
            ||:|..:...|||..::.|......|.:|:..:.:||  |....|:.||:||...||:::.|.|:
  Rat    13 SSQDPKYPVENLLNPDSHKGPWLSCPRDKTGQLKVEFQLERAVPISYIDVGNCGCAFLQIDVGRS 77

  Fly    76 GCQAD-DFRELLLSSSFMTPIESKNSSNPNRVRCFSSTSLAESALPEKWKLLQIVCTQPFNRHVP 139
            ....| .|..||.::..|:..:||...|.:.||.|........|..|.|..|::.|:|||.||..
  Rat    78 SWPLDRPFVTLLPATMLMSLTDSKEGKNRSGVRMFKDDDFLIPASGESWDRLRLTCSQPFTRHQS 142

  Fly   140 YGLSFVKVH-VVAAAAPKVKSLVPQGVMQFGTFKLREESPDSETDNQVNRFHSWKKQTQHKSPAI 203
            :||:|::|. .:.:.:..||.               ..||.|...||    :|..|.....||.:
  Rat   143 FGLAFLRVRSSLDSLSDPVKD---------------PSSPGSSGLNQ----NSSDKLESDPSPWL 188

  Fly   204 SATSTAAAIRDAGSTALRRLSA--GKVSSLAASPKTSTSPSPVLNALRSVSPTPLDAKPLDRNRA 266
            :..|..........|:.:.:||  |.:..|        .|.|:..|.|.|......|.|     |
  Rat   189 TNPSIRRTFFPDPQTSTKEISALKGMLKQL--------QPGPLGRAARMVLSAAHKAPP-----A 240

  Fly   267 SLLFGDDDEDVKDAEVNAKKQRLSKHLEADKDRRRLEQEKERESRKKKSSRHSLDKSISKEDKPP 331
            |::..::.....|          |.|.|      |.|...|..:||..:||....|  .:|.:.|
  Rat   241 SVVSPNNSHGEPD----------SSHPE------RAEPRAEEPNRKNNASRGKRRK--VQEQRRP 287

  Fly   332 AKEHNSSSREKSTAKEEKEQLRKEERS 358
            ....:|....::|.:.::.|.|.:.:|
  Rat   288 LSSSSSQPNRRATGRTKQRQQRPQAKS 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
XRCC1	NP_572217.1	XRCC1_N	1..144	CDD:280080	44/133 (33%)
XRCC1	NP_572217.1	BRCT	420..494	CDD:278934
Xndc1	NP_001316819.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248725at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920