Protein Alignment CG3309 and Dennd6b

DIOPT Version :10

• Sequence 1: NP_572216.1
• Gene: CG3309 / 31450
• FlyBaseID: FBgn0029756
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_081357.2
• Gene: Dennd6b / 69440
• MGIID: 1916690
• Length: 585
• Species: Mus musculus
• Alignment Length: 623
• Identity: 270/623 - (43%)
• Similarity: 376/623 - (60%)
• Gaps: 76/623 - (12%)

  Fly    28 ATNSNSEPSAS-----DWVNFSQWMHCFCVVTFDLNLGQALEHVYPPAFMPSDQEVSNICYMAFP 87
            ||.|:|...|:     .|..||.|:.|.|||||||.||||||.|||..|..:|:|.|:|||:|||
Mouse    18 ATRSSSSGRAARTAEMPWARFSAWLECVCVVTFDLELGQALELVYPSDFRLTDKEKSSICYLAFP 82

  Fly    88 DSNSGCMGDTKFHMRLRCTTRRDSL-----PGYNAECSPALRQDGSHYWGFVYFRQKRDANLPRG 147
            ||:|||:|||:|..|:|....:.||     ..||.:...||:::.:||.|:|||||.:|:::.||
Mouse    83 DSHSGCLGDTQFSFRMRQCGGQRSLWQVDDRSYNNKAPLALQREPAHYLGYVYFRQVKDSSVKRG 147

  Fly   148 YFQKSFIIITRLPFFNLYYDILSQLAPRYFEEGTDVLRLASEQINRQWPGLRVGKPLQLPLLDCS 212
            |||||.::::||||..|:..:||.:||.|||:....|.....:|: |||....|:.|.||::...
Mouse   148 YFQKSLVLVSRLPFVRLFQSLLSLIAPEYFEKLAPCLEAVCNEID-QWPAPVPGQTLNLPIMGVV 211

  Fly   213 YQICIPRTSSSRKSTADGGIAGGAVESPPAMA----ACPAAKVLASVNEIELFRSLDFVMEQLYT 273
            .|:.||......:|            |||...    ..||..||.||:|::|||....|:..:.|
Mouse   212 IQVRIPSRVDKLES------------SPPKQCDQENLLPAPVVLTSVHELDLFRCFRPVLTHVQT 264

  Fly   274 LWELVITAEPIVVVGTSPADCSHMVQTLLAMIAPLEYCAEARPYFTIHDSEFREFTQECSSKTTL 338
            ||||::..||:||:..||...|.:|..|.:.:.||::|.:.|||||||||||:|.|....:.
Mouse   265 LWELMLLGEPLVVLAPSPDVSSELVLALTSCLQPLKFCCDFRPYFTIHDSEFKELTTRTQAP--- 326

  Fly   339 PACILGVTNPFFVKLLKDWPHMLRLVDNQKNMQQQQHLLLGQKHARNIASATSFSSSTELGGRIA 403
            |..:||||||||:|.|:.|||:||:.:.:                          .|.:|..::.
Mouse   327 PNVVLGVTNPFFIKTLQHWPHVLRIGEPK--------------------------MSGDLPKQVK 365

  Fly   404 LKSNTNLNGSSSSSNGSGDASSAGLHSKYRPYLKKDKALIKKVLLGMKTKRPEHVQTALIRRHLL 468
            ||..:.|....         :..||::.|..:|.:||||:|::|.|::.|||..||:||:|||||
Mouse   366 LKKPSRLKTLD---------TKPGLYTSYTAHLHRDKALLKRLLKGVQKKRPWDVQSALLRRHLL 421

  Fly   469 ELTQSFMIPLERYMASLMPLQKDISPFKSAPNANSFKLDDFLGTLETAGPQLTSPLKGDWKGLYR 533
            ||||||:||||.||||||||||:|:|:||.|....|:.||||.:||.||||||..|||||.||||
Mouse   422 ELTQSFIIPLEHYMASLMPLQKNITPWKSPPQICPFRQDDFLRSLEHAGPQLTCILKGDWLGLYR 486

  Fly   534 RFFRSPNFRGWYGARHRELQLTLQDLQLQALSVANLEHWAHDKQEVEIIDMILKLKQKLNLYGDK 598
            |||:||:|.|||..||:|:...|:.|.|:|:..||:|.|..||.|||::|::|||::||
Mouse   487 RFFKSPHFDGWYRQRHKEMAQKLEALHLEAICEANIEAWMKDKSEVEVVDLVLKLREKL------ 545

  Fly   599 ATQLEGN----NGSTQQQIRAQIECMKGLLPPDLKNVV 632
             .:.:|:    ...|.|:.:..|:.:.|.||.||:.|:
Mouse   546 -VRAQGHQLPVKEVTLQRAQLYIDTVIGSLPKDLQAVL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3309	NP_572216.1	Avl9	49..>192	CDD:430832	73/147 (50%)
		SPA	270..368	CDD:454797	46/97 (47%)
Dennd6b	NP_081357.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		4/6 (67%)
		DENN	151..>311	CDD:472208	62/172 (36%)
		SPA	250..356	CDD:454797	50/134 (37%)