Protein Alignment CG3309 and Dennd6a

DIOPT Version :9

• Sequence 1: NP_572216.1
• Gene: CG3309 / 31450
• FlyBaseID: FBgn0029756
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001127937.1
• Gene: Dennd6a / 211922
• MGIID: 2442980
• Length: 605
• Species: Mus musculus
• Alignment Length: 634
• Identity: 250/634 - (39%)
• Similarity: 367/634 - (57%)
• Gaps: 64/634 - (10%)

  Fly    13 SLDTTERE-REHQNVDATNSNSEPSASD--------WVNFSQWMHCFCVVTFDLNLGQALEHVYP 68
            |||....| ||...:.|.....|....|        |..||.|:||.|||.|||.||||:|.:||
Mouse    16 SLDEAGAEGREAAALAAAGVALEDEEEDDGRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYP 80

  Fly    69 PAFMPSDQEVSNICYMAFPDSNSGCMGDTKFHMRLRCTT-RRDS----LPGYNAECSPALRQDGS 128
            .....:|:|.:||||::||||||||:|||:|..|.|.:: ||.|    |..::.:....|::|.:
Mouse    81 QHSKLTDKEKTNICYLSFPDSNSGCLGDTQFCFRFRQSSGRRVSLHCLLDEFDKDLPVYLKKDPA 145

  Fly   129 HYWGFVYFRQKRDANLPRGYFQKSFIIITRLPFFNLYYDILSQLAPRYFEEGTDVLRLASEQINR 193
            :::|:|||||.||..|.|||||||.::|::||:.:.::.:|.|:||.|||:....|..|...::|
Mouse   146 YFYGYVYFRQVRDKTLKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDR 210

  Fly   194 QWPGLRVGKPLQLPLLDCSYQICIPRTSSSRKSTADGGIAGGAVESPPAMAACPAAKVLASVNEI 258
             ||....||.|.||::....::.|| |...:..|..       :......|....:.:|.:|:|:
Mouse   211 -WPAPVPGKTLHLPIMGLVMKVRIP-TCHDKPGTTQ-------MVQLTQQADTHTSIILPTVHEV 266

  Fly   259 ELFRSLDFVMEQLYTLWELVITAEPIVVVGTSPADCSHMVQTLLAMIAPLEYCAEARPYFTIHDS 323
            :|||....|......|||||:..||:||:..||::.|..|..|:..|:||:|.::.|||||||||
Mouse   267 DLFRCFCPVFLHSQMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDS 331

  Fly   324 EFREFTQECSSKTTLPACILGVTNPFFVKLLKDWPHMLRLVDNQKNMQQQQHLLLGQKHARNIAS 388
            ||:|:|....:.   |:.|||||||||.|.|:.|||::|:.|
Mouse   332 EFKEYTTRTQAP---PSVILGVTNPFFAKTLQHWPHIIRIGD----------------------- 370

  Fly   389 ATSFSSSTELGGRIALKSNTNLNGSSSSSNGSGDASSAGLHSKYRPYLKKDKALIKKVLLGMKTK 453
               ...:.|:..::.:|...||....         |..|:::.|:|||.:|:.:||::..|::.|
Mouse   371 ---LKPAGEIPKQVKVKKLKNLKTLD---------SKPGVYTSYKPYLNRDEEIIKQLQKGIQQK 423

  Fly   454 RPEHVQTALIRRHLLELTQSFMIPLERYMASLMPLQKDISPFKSAPNANSFKLDDFLGTLETAGP 518
            ||...|:.::||:.|||||||:||||||:||||||||.|||:||.|....|..::|:.|||..||
Mouse   424 RPSEAQSVILRRYFLELTQSFIIPLERYVASLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGP 488

  Fly   519 QLTSPLKGDWKGLYRRFFRSPNFRGWYGARHRELQLTLQDLQLQALSVANLEHWAHDKQEVEIID 583
            ||||.:||||.||||:|.:||||.||:..|.:|:...|:.|.|:||...:|..|.....|||.:|
Mouse   489 QLTSGIKGDWIGLYRQFLKSPNFDGWFKTRRKEMTQKLEALHLEALCEEDLLLWIQKHTEVETVD 553

  Fly   584 MILKLKQKLNLYGDKATQLEGNNGSTQQQIRAQIECMKGLLPPDLKNVV 632
            ::||||.||...|.::..::.:   |.:::|..|:.:...||.||:.::
Mouse   554 LVLKLKNKLLQAGRESLPVKPD---TVEKLRTHIDAIILALPDDLQGIL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3309	NP_572216.1	SPA	270..368	CDD:285780	48/97 (49%)
Dennd6a	NP_001127937.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		3/3 (100%)
		DENN	168..356	CDD:299760	74/199 (37%)
		SPA	267..370	CDD:285780	51/105 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849464
Domainoid	1	1.000	218	1.000	Domainoid score	I2645
eggNOG	1	0.900	-	-		E1_KOG2432
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13503
Inparanoid	1	1.050	484	1.000	Inparanoid score	I1429
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55704
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003104
OrthoInspector	1	1.000	-	-		otm44081
orthoMCL	1	0.900	-	-		OOG6_102254
Panther	1	1.100	-	-	O	PTHR13677
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3543
SonicParanoid	1	1.000	-	-		X2076
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790