Protein Alignment Mcm3 and MCM2

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_175112.2
• Gene: MCM2 / 841056
• AraportID: AT1G44900
• Length: 936
• Species: Arabidopsis thaliana
• Alignment Length: 663
• Identity: 234/663 - (35%)
• Similarity: 355/663 - (53%)
• Gaps: 69/663 - (10%)

  Fly     1 MAHEGEQFIKDIQREYVDFL------DDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRA 59
            |..|..:|   |.:::.|||      .:|.....|...:.:|::.....|.::..:....:|..|
plant   210 MRDEVRRF---IAKKFKDFLLTYVKPKNENGDIEYVRLINEMVSANKCSLEIDYKEFIHVHPNIA 271

  Fly    60 LGLLSNAADEQLAFGRALKEYASTV----DPGYAKMHEDLFVGFEGCFGNRHVTPRSLTSIYLGN 120
            :.|    ||........::|.:..|    .|.|..:|..::|.......|..:  |::..|:|..
plant   272 IWL----ADAPQPVLEVMEEVSEKVIFDLHPNYKNIHTKIYVRVTNLPVNDQI--RNIRQIHLNT 330

  Fly   121 MVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKDEDGNLLETEY 185
            |:.:.|:||:.|.:.|::.:..:.|.....|:...:.:  |:..|..|:....:.:....:..|.
plant   331 MIRIGGVVTRRSGVFPQLQQVKYDCNKCGAVLGPFFQN--SYSEVKVGSCSECQSKGPFTVNVEQ 393

  Fly   186 GLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYR-----CLPGKR 245
              ::|:::|.|||||.|...|||:|||..:::..:||:|..:||:.:::.|.|.     .|..|.
plant   394 --TIYRNYQKLTIQESPGTVPAGRLPRHKEVILLNDLIDCARPGEEIEVTGIYTNNFDLSLNTKN 456

  Fly   246 GGYTSGTFRTVLLANNISLLSKESNL----DISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHA 306
            |   ...|.||:.||.:   :|:.:|    .:::||....::|:|:..|.|.:.||:||||:||.
plant   457 G---FPVFATVVEANYV---TKKQDLFSAYKLTQEDKTQIEELSKDPRIVERIIKSIAPSIYGHE 515

  Fly   307 YVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGV 371
            .:|.|:...:.||.||.:....||||||||||:|||..||||.|:||..|..||:.|||:|:|.|
plant   516 DIKTALALAMFGGQEKNIKGKHRLRGDINVLLLGDPGTAKSQFLKYVEKTGQRAVYTTGKGASAV 580

  Fly   372 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAS 436
            ||||||..|..|.|..||.||:||||||:..|||||||:|.||.:|||.|||..::||||||..|
plant   581 GLTAAVHKDPVTREWTLEGGALVLADRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAGIVTS 645

  Fly   437 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHR 501
            |.|||||:||||||.||||..|:..:|:.|.|.:|||||:|.|:.||:|...|:|:::.||..|.
plant   646 LQARCSVIAAANPVGGRYDSSKSFAQNVELTDPILSRFDILCVVKDVVDPVTDEMLAEFVVNSHF 710

  Fly   502 YRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYI 566
            ...||         |....||           |.|     |. :.|.|.....::|....::||:
plant   711 KSQPK---------GGKMEDS-----------DPE-----DG-IQGSSGSTDPEVLPQNLLKKYL 749

  Fly   567 HIAKC-MKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKS 630
            ..:|. :.|||||...:.:...|:.||.:......|:    |..|.||::||:|.||||..:.:.
plant   750 TYSKLYVFPKLGELDAKKLETVYANLRRESMNGQGVS----IATRHLESMIRMSEAHARMHLRQY 810

  Fly   631 VTIDDAHAAIELV 643
            ||.:|.:.||.::
plant   811 VTEEDVNMAIRVL 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	18/97 (19%)
		MCM	106..648	CDD:214631	211/548 (39%)
MCM2	NP_175112.2	MCM2_N	67..>138	CDD:403724
		MCM_N	220..313	CDD:464206	18/96 (19%)
		MCM	320..828	CDD:214631	211/546 (39%)