Protein Alignment Mcm3 and mcm3

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001039231.1
• Gene: mcm3 / 734092
• XenbaseID: XB-GENE-5857845
• Length: 809
• Species: Xenopus tropicalis
• Alignment Length: 824
• Identity: 518/824 - (62%)
• Similarity: 637/824 - (77%)
• Gaps: 35/824 - (4%)

  Fly     6 EQFIKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADEQ 70
            :|.:::.||||:||||||||||||...|:|||:|...|||||||||::||.:||..|::||.:..
 Frog    11 DQEMREAQREYLDFLDDEEDQGIYQSKVRDMISENQYRLIVNVNDLRKKNEKRANMLMNNAFEGL 75

  Fly    71 LAFGRALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPRSLTSIYLGNMVCVEGIVTKVSLIR 135
            :||.||||::.:::|..|||.:|:.::|.||.|||:|||||:|||..|..:|||||||||.||:|
 Frog    76 IAFQRALKDFVASIDGTYAKQYEEFYIGLEGSFGNKHVTPRTLTSRCLSCIVCVEGIVTKCSLVR 140

  Fly   136 PKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQE 200
            |||||||||||.|:|.:|||||||||.||.||.|.||||||:.|.||||||||:||||||:||||
 Frog   141 PKVVRSVHYCPATKKTIERKYTDLTSLEAFPSSAVYPTKDEENNPLETEYGLSIYKDHQTITIQE 205

  Fly   201 MPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANNISLL 265
            ||||||||||||||||:.||||||:.|||||||::|:|||||.|:.||||.:|||:|:|.|:..:
 Frog   206 MPEKAPAGQLPRSVDIILDDDLVDKVKPGDRVQVIGTYRCLPSKQNGYTSASFRTILIACNVIQM 270

  Fly   266 SKESNLDISREDIMLCKKLAKNN--DIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGT 328
            |||.....|.:|:...||.:|::  ||||.||:|||||||||.|:|:||||:|||||||:|.|||
 Frog   271 SKEVTPVFSADDLAKIKKFSKSHSKDIFEQLSRSLAPSIHGHLYIKKAILCMLLGGVEKVLDNGT 335

  Fly   329 RLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAM 393
            |:||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||
 Frog   336 RIRGDINVLLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAM 400

  Fly   394 VLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYK 458
            ||||||||||||||||||:||||||||||||||||:||||||.||||||||||||||||||||||
 Frog   401 VLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYK 465

  Fly   459 TPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSL 523
            |||:||||||||||||||||:|||.:|.:.|:.|||||:||||||...|.||:.:.:||: .|.|
 Frog   466 TPMDNIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAAGEQDGDAMPLGSA-VDIL 529

  Fly   524 SFVS---SSEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIA 585
            :...   :|||:::.:||||:|:|||| .::|.||||||||||||:|:||..||.|.::|...||
 Frog   530 ATNDPNVTSEEQQELQVYEKHDSLLHG-VKKRKEKILSVEFMRKYVHVAKIFKPVLTQEAASFIA 593

  Fly   586 NEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKK 650
            .||||||:|:.:.||||||.|:||||||||||||||||:.||||:|.:.||.|||||||:|||||
 Frog   594 EEYSRLRNQDQLSTDVARTSPVTARTLETLIRLSTAHAKVRMSKTVQLQDAEAAIELVQYAYFKK 658

  Fly   651 VLDKDRPSKRRRNSGSDAEDD-----NGEASSQRSPSRRSKRTRTATVGADSDEEDIEPPQPDAG 710
            ||:|:: .:|||:..||.|.:     :|||..:|. .||::...:......||.||..|
 Frog   659 VLEKEK-KRRRRDEDSDTEGEQQTQPDGEAKKRRK-KRRAQEGESHDPYEFSDTEDETP------ 715

  Fly   711 DLTRRETRRSLPARSVAMLMASPSSEEQSVATSTTEPAIISDARLGEFKNNLQRLFREAREQSLA 775
                           |.....:|.:.::.:.|.::....:|..||..||:.|...|:.|..||:|
 Frog   716 ---------------VVHTPKTPVNGQEEMETDSSAKPGLSGERLKAFKSALLGAFKSAHAQSIA 765

  Fly   776 LARITTAINVGSQEPFTAGEIEAAVHRMTEDNQIMVADDIVFLI 819
            :..:..|||..:..||:..|::||:..|.|.|.|||:|:|||||
 Frog   766 MEALMEAINKRNDSPFSQAEVKAALELMEEANHIMVSDNIVFLI 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	49/87 (56%)
		MCM	106..648	CDD:214631	405/546 (74%)
mcm3	NP_001039231.1	MCM_N	18..106	CDD:464206	49/87 (56%)
		MCM	111..656	CDD:214631	405/546 (74%)
		Arginine finger	479..482		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	664..741		20/99 (20%)