Protein Alignment Mcm3 and Mcm9

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001403310.1
• Gene: Mcm9 / 499437
• RGDID: 1560557
• Length: 1128
• Species: Rattus norvegicus
• Alignment Length: 799
• Identity: 218/799 - (27%)
• Similarity: 344/799 - (43%)
• Gaps: 201/799 - (25%)

  Fly    32 HVKDMIAEKSKR-------LIVNVNDLKRKN----------PQRALGLLSNAADEQLAFGRALKE 79
            |..|::....:|       |:||...|...|          |...|.:..:|....     ||..
  Rat    21 HKNDILLILKERDEDAHYPLVVNAMTLFETNMEIGDYFTVFPNEVLTVFDSALRRS-----ALAV 80

  Fly    80 YASTVDPGYAKMHEDLFVGFEG---C--FGNRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRP--- 136
            ..|..:|....|.::|.....|   |  ....|: |::..   :|:.:.|.|.|.:.||::.
  Rat    81 LQSLPEPEGLSMKQNLHARISGLPVCPELVREHI-PKTKD---VGHFLSVTGTVIRTSLVKVLEF 141

  Fly   137 ---------KVVRSV------HY-------CPNTRKVMERKYTDLTSFEAVPSGAAYPTKDEDGN 179
                     |.|.:|      :|       ||::......|:|.|:...|.|:..
  Rat   142 ERDYMCNKCKYVFTVKADFEQYYTFSRPSSCPSSDTCDSSKFTCLSDLSASPARC---------- 196

  Fly   180 LLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVG-------- 236
                       :|:|.:.|||..::...|.:|||:.::.:|||||.||.||.:.|.|
  Rat   197 -----------RDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVMQRWKP 250

  Fly   237 ---SYRCLPGKRGGYTSGTFRTVLLANNISLLSKESNLDISREDIMLCKK-------------LA 285
               ..||           ....||.||.:.:.:::|:..:..||   .:|             .|
  Rat   251 FQRDMRC-----------EVEIVLKANYVQVNNEQSSGMVMDED---ARKEFEDFWEHYKSDPFA 301

  Fly   286 KNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLL 350
            ..|:|.    .||.|.:.|...||.|:..:|.||:::....|||:||:.::||:|||...|||.|
  Rat   302 GRNEIL----ASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHLLLVGDPGTGKSQFL 362

  Fly   351 RYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRT 415
            :|.....||::.|||.||:..|||  ||..:::||..|||||:||||.|:.|||||:.:.:.|||
  Rat   363 KYAAKITPRSVLTTGIGSTSAGLT--VTAVKDSGEWNLEAGALVLADAGLCCIDEFNSLKEHDRT 425

  Fly   416 AIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVM 480
            :|||.|||..::::|||:...||.|.::|||.|| .|:||..::...||.|...|||||||:.|:
  Rat   426 SIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPQESVSVNIALGSPLLSRFDLILVL 489

  Fly   481 LDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALL 545
            ||..:.|.|::||..::         |..|.|
  Rat   490 LDTRNEDWDRIISSFIL---------ENKGYP--------------------------------- 512

  Fly   546 HGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITAR 610
                 .:.|.:.|:|.|:.|..:.:.:.|.|.:.:.:.:...|...|..::  .:.|||   |.|
  Rat   513 -----SKSENLWSMEKMKTYFCLIRNLHPTLSDVSNQVLLRYYQMQRQSDS--RNAART---TIR 567

  Fly   611 TLETLIRLSTAHARARMSKSVTIDDAHAAIELVQF------------AYFKKVLDKDRPSKRRRN 663
            .||:||||:.||||.....:||::||...:.:::.            |......:..|...||:
  Rat   568 LLESLIRLAEAHARLMFRSTVTLEDAITVVSVMESSMQGGALLGGVNALHTSFPESPRAQYRRQ- 631

  Fly   664 SGSDAEDDNGEASS-QRSPSRRSKRTRTATVGADSDEEDIEPPQPDAGDLTRRETRRSLPARSVA 727
              .:...:..|..| .:...||.:|.:.     :||:.....|:.:|...:.|...|..|.
  Rat   632 --CELILEKLELQSLLQEELRRLERLQN-----ESDQCQPHSPEVEAAPGSCRNDPRDRPG---- 685

  Fly   728 MLMASPSSEEQSVATSTTE 746
              :.:|:.:|||.:.|..|
  Rat   686 --LRTPTQQEQSCSWSPAE 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	17/85 (20%)
		MCM	106..648	CDD:214631	178/602 (30%)
Mcm9	NP_001403310.1	MCM_OB	116..243	CDD:465381	36/150 (24%)
		MCM9	305..603	CDD:350666	126/356 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	657..737		13/57 (23%)
		PHA03307	667..>1014	CDD:223039	11/42 (26%)