Protein Alignment Mcm3 and mcm4

DIOPT Version :9

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001005655.1
• Gene: mcm4 / 448137
• XenbaseID: XB-GENE-1011481
• Length: 863
• Species: Xenopus tropicalis
• Alignment Length: 880
• Identity: 247/880 - (28%)
• Similarity: 386/880 - (43%)
• Gaps: 246/880 - (27%)

  Fly     6 EQFIKDIQREYVDFLDDEED-------QGIYAGHVKD--MIAEKSKRLIVNVN---------DLK 52
            |:|.:.:|| ::|.|..||:       :.||...:::  ::.|.    .:||:         ||.
 Frog   164 EKFQRFVQR-FIDPLAKEEENVGLDLNEPIYMQRLEEINVVGEP----FLNVDCDHLRSFDQDLY 223

  Fly    53 RK---NPQRALGLLSNAADEQLAFGR---ALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPR 111
            |:   .||..:.....||:| :.|.|   ::.|:...|.|..|....::               |
 Frog   224 RQLVCYPQEVIPTFDMAANE-IFFERYPDSILEHQIQVRPYNALKTRNM---------------R 272

  Fly   112 SLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCP----NTRKVMER---------KYTDLTSFE 163
            ||....:..::.:.|:|.:.|.|.|::..:...|.    .||..::|         |:.:.|...
 Frog   273 SLNPEDIDQLITISGMVIRTSQIIPEMQEAFFKCQVCAFTTRVEIDRGRISEPSVCKHCNTTHSM 337

  Fly   164 AVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKP 228
            |:                  .:..|::.|.|.:.:||.||..||||.|.:..:...:||||:.:|
 Frog   338 AL------------------IHNRSMFSDKQMIKLQESPEDMPAGQTPHTTILYGHNDLVDKVQP 384

  Fly   229 GDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANNISLLSKESNLDI-------------------- 273
            ||||.:.|.||.:|          .|......|:..:.| :::|:
 Frog   385 GDRVNVTGIYRAVP----------IRVNPRVRNVKSVYK-THIDVIHYRKTDAKRLHGIDEDTEQ 438

  Fly   274 ---SREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTR--LRGD 333
               :.|.:.:.|:||...||:|.|:.:|||||:.|..:|:.||..|.||..|...:..|  .|.:
 Frog   439 KMFTEERVAMLKELAAKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE 503

  Fly   334 INVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADR 398
            :|:||.|||..:|||||:||.|..||...|:|:|||.|||||.|..|.||.:..|:.||:||:|.
 Frog   504 VNILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDN 568

  Fly   399 GVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMEN 463
            |:.||||||||::..|:.:||||||..::|:||||...||||.|||||||||..:::..||.:||
 Frog   569 GICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPVESQWNPKKTTIEN 633

  Fly   464 IGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSS 528
            |.|..:|||||||:|:|||..|...|:.::.|:|.:: |::.::                    .
 Frog   634 IQLPHTLLSRFDLIFLMLDPQDETYDRRLAHHLVALY-YQSEEQ--------------------M 677

  Fly   529 SEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRS 593
            .||..|..|.:.|                 :.:.|.|::      |:|||:|.:|:...|..:|.
 Frog   678 KEEHLDMAVLKDY-----------------IAYARTYVN------PRLGEEASQALIEAYVDMRK 719

  Fly   594 QEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVLDKDRPS 658
            ..:....|: ..|   |.||:|||||.|||:.|.|..|...|...|..|.:.|.
 Frog   720 IGSGRGMVS-AYP---RQLESLIRLSEAHAKVRFSSKVETIDVEEAKRLHREAL----------- 769

  Fly   659 KRRRNSGSDAEDDNGEASSQRSPSRRSKRTRTATVGADSDEEDIEPPQPDAGDLTRRETRRSLPA 723
               :.|.:|                    .||..|                 |::...|..|..|
 Frog   770 ---KQSATD--------------------PRTGIV-----------------DISILTTGMSATA 794

  Fly   724 R----SVAMLMASPSSEEQSVATSTTEPAIISDARLGEFKNNLQRLFREAREQSLALARITTAIN 784
            |    .:|.::      ::.:.:....||:           ..|:||.:.|.||.|..
 Frog   795 RKRKEELAQVL------KKLIQSKGKTPAL-----------KYQQLFEDLRGQSDAAV------- 835

  Fly   785 VGSQEPFTAGEIEAAVHRMTEDNQIMVADDIVFLI 819
                   |....:.|:|.:.:::.:.|....|.|:
 Frog   836 -------TKDMFDEALHALADEDYLTVTGKTVRLL 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	18..101	CDD:379644	23/106 (22%)
		MCM	106..648	CDD:214631	194/579 (34%)
mcm4	NP_001005655.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..121
		PHA03307	<3..>122	CDD:223039
		MCM_N	166..264	CDD:379644	25/103 (24%)
		MCM	267..770	CDD:214631	194/608 (32%)
		Arginine finger	642..645		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920