Protein Alignment Mcm3 and Mcm7

DIOPT Version :9

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Alignment Length: 697
• Identity: 232/697 - (33%)
• Similarity: 349/697 - (50%)
• Gaps: 118/697 - (16%)

  Fly     4 EGEQFIKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAAD 68
            :..:.||....|:....||.:.:.:|...:..:...:...:.::::||...|...|..::.|...
  Fly     8 QDRESIKTFLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVVDNCRR 72

  Fly    69 EQLAFGRALKEYASTVDPGY------AKMHEDLF------------------------------- 96
            ....|...:.|..    |.|      ||...|::
  Fly    73 YTSIFSDVIAELL----PSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMKR 133

  Fly    97 --VGFEGCFGNRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDL 159
              |||:.....:..:.|.:.:.::|.:|.|.||||:.:.::|.:|.:.:.|.   :.....|..:
  Fly   134 FEVGFKPLSTEKAHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCD---RCGSETYQPV 195

  Fly   160 TSFEAVPSGAAYPTKD----EDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDD 220
            .|....|.... |:.|    :.|..|..:...|.:...|.:.:||..::.|.|.:|||:.|:|..
  Fly   196 NSLSFTPVHDC-PSDDCRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRG 259

  Fly   221 DLVDRCKPGDRVQIVGSYRCLPGKRGGYT-------SGTFRTVLLANNISLLSKESNLDISREDI 278
            ::....:|||.:.:.|.:  ||..|.|:.       |.||   |.|:.|..::|  |.:||.:|.
  Fly   260 EVTRMAQPGDHIVVSGVF--LPLMRTGFAQMIQGLLSETF---LQAHRIICINK--NDEISDKDA 317

  Fly   279 ML----CKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLI 339
            .|    .::||: :|.:|.|:.||||.|:||..||:|:|.||:|||:| .|:|.::||:||:.|:
  Fly   318 ELTPEELEELAQ-DDFYERLATSLAPEIYGHLDVKKALLLLLVGGVDK-RPDGMKIRGNINICLM 380

  Fly   340 GDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCID 404
            |||.|||||||.|:...|.|:..|||||||||||||||..|..|||..||.||:||||:||.|||
  Fly   381 GDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGVCCID 445

  Fly   405 EFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDS 469
            |||||:|.|||||||||||..::|:||||..:||||.|:||||||.:|||:..:|..:||.|..:
  Fly   446 EFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFGRYNPRRTVEQNIQLPAA 510

  Fly   470 LLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKD 534
            ||||||||:::.|..|.|.|..::.|:..:|.
  Fly   511 LLSRFDLLWLIQDKPDRDNDLRLAKHITYVHS--------------------------------- 542

  Fly   535 TEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVET 599
                       |.|......|.|.:..||:||::.|...|.:.::..:.|...|..||.:...:.
  Fly   543 -----------HSKQPPTRVKALDMNLMRRYINLCKRKNPTIPDELTDYIVGAYVELRREARNQK 596

  Fly   600 DVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFA 646
            |:..|   :||.|..::|||||.||.|:|.||..||...|:.|::.:
  Fly   597 DMTFT---SARNLLGILRLSTALARLRLSDSVEKDDVAEALRLLEMS 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	18..101	CDD:379644	18/121 (15%)
		MCM	106..648	CDD:214631	211/556 (38%)
Mcm7	NP_523984.1	MCM_N	13..97	CDD:379644	16/87 (18%)
		MCM	145..641	CDD:214631	211/556 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446135
Domainoid	1	1.000	52	1.000	Domainoid score	I661
eggNOG	1	0.900	-	-		E1_COG1241
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D15169at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11630
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850