Protein Alignment Mcm3 and LOC3290529

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_061502321.1
• Gene: LOC3290529 / 3290529
• VectorBaseID: AGAMI1_014641
• Length: 1119
• Species: Anopheles gambiae
• Alignment Length: 925
• Identity: 247/925 - (26%)
• Similarity: 403/925 - (43%)
• Gaps: 209/925 - (22%)

  Fly    10 KDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADE----- 69
            |...:|..|.|::.:|    ..||.         :.||:..|:|:.||....:..:...|
Mosquito     7 KHYAQEITDLLNNSDD----LQHVS---------IHVNLTQLQREQPQLFARIFQDTQTELARWN 58

  Fly    70 --QLAFGRALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPRSL-TSIY-----LGNMVCVEG 126
              .|...::|.|....:|||: ::.|:..|.|.    |..|:|..| .|.|     :|..:.|:|
Mosquito    59 ECLLRAQKSLIEGNLFLDPGF-QVKENCHVRFV----NVPVSPAELRKSAYPNNDSVGQFLQVKG 118

  Fly   127 IVTKVSLIRPKVVRSVHYCPNTRK--VMERKYTDLTSFEAVPSGAAYPTKDEDG-----NLLETE 184
            .|.::|..|....|..:.|...::  |:|.:|.....||  |.|.. |...|.|     ..:..:
Mosquito   119 SVIRMSSSRFLEYRREYACTRCKQKVVIEAEYCKSYVFE--PPGPC-PNAREAGCRGQLQPVSAQ 180

  Fly   185 YGLSVYKDHQTLTIQE-MPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVG--SYRCLPGKRG 246
            ....:.:|:|.:.||| |.|:    .:|.|:.:..:|||||.|:|||.|.:.|  .:|..|...|
Mosquito   181 PQPELCRDYQEIRIQEIMSER----NVPASLVVTLEDDLVDSCQPGDCVTVCGPIEHRWKPPTVG 241

  Fly   247 GYTSGTFRTVLLANNISLLSKESNLDISRE--DIMLC------KKLAKNNDIF--ELLSKSLAPS 301
            ..|..|.  .:.||:::  .:||....:::  :.:||      :.|.:..::.  :||.:|:||:
Mosquito   242 RRTEVTI--AMRANSVA--REESKASWAKDLPEHLLCVPAEWQEVLREIGELAARDLLVQSIAPA 302

  Fly   302 IHGHAYVKQAILCLLLGGVEKILPNGTR---LRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPT 363
            |.|...||.||...|....|:: .:|.:   :||..::||:|||.:||||||:|....|.||:.|
Mosquito   303 IRGMYPVKLAIALALASCTERV-GDGEQQATVRGHSHLLLVGDPGLAKSQLLKYASEIASRAVYT 366

  Fly   364 TGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTI 428
            ||.|.|..|||||...|:  ||.:|||||:||||.|:.|||||:.|.:.|:.:|||.|||..:::
Mosquito   367 TGMGCSSAGLTAAAVKDE--GEWQLEAGALVLADGGICCIDEFNLMRETDKASIHEAMEQQTISV 429

  Fly   429 SKAGIHASLNARCSVLAAANP--VYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQM 491
            :|||:...|:.||.||||.||  :|...|......||||:...||||||::.::.||..:|.|..
Mosquito   430 AKAGMVCKLSTRCVVLAATNPKNLYTMSDGLGKSAENIGIGGPLLSRFDMVMILKDVRAADWDAD 494

  Fly   492 ISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHEKI 556
            |::|::                      |.:|    ..||:   |.:|       |:. .|.:::
Mosquito   495 IANHLL----------------------AQAL----LDEER---ECFE-------GEG-NRTDRV 522

  Fly   557 LSVEFMRKYIHIA--KCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLS 619
            ...|..:..:|.|  |...|::..:|...:...|...||..  ..|..||   |.|.|::|.||:
Mosquito   523 AHWELEKLQLHFAAIKDFHPRVSPEANVILGAYYKACRSDP--YRDPTRT---TVRLLDSLFRLA 582

  Fly   620 TAHARARMSKSVTIDDAHAAIELVQFA-------------------------------------- 646
            .||||..:...||..||...|:|::.:
Mosquito   583 QAHARLLLRNEVTPIDAITIIQLMEASWGFGKIGIPTYDLIKAQLPLGPEQGTIDRLLDVLNLHG 647

  Fly   647 ------------------YFKKVLDKDRP----SKRRRNSGSDAEDDNGEASSQRSPSRRSKRTR 689
                              |.:::::|.:.    .:|.:::.:.....:|:..||::.|      .
Mosquito   648 VVQDTATVRPIDPNILRRYHRELIEKQKRKQLIEQREQSTDTGRIVSDGDDRSQQTVS------S 706

  Fly   690 TATVGADSDEEDIE-----PPQPDAGDLTRRETRRSLPARSVAMLMASPSSEEQS---------- 739
            |.|...|..|:.::     ||......|..:...:.|..::.|...:..:||:.:
Mosquito   707 TLTTVNDFREQQLKTVPQVPPTSSKYALNPKANFKKLRKQTTAKATSEANSEDSTSRGARKRKRA 771

  Fly   740 ---VATSTTEPAIISDARLGEFKNNLQRLF--REAREQSLALARITTAINVGSQEPFTAGEIEAA 799
               |....|..|.:.||.||....:|::.|  .||::.:.:...:...........|:|
Mosquito   772 TNEVEEDLTLKAPLDDAALGNLLGSLRKSFGASEAQDPAASATEMAKTQTQSKDLSFSA------ 830

  Fly   800 VHRMTEDNQIMVADD 814
               :.:.:||...||
Mosquito   831 ---LLDTSQIFEDDD 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	22/94 (23%)
		MCM	106..648	CDD:214631	188/630 (30%)
LOC3290529	XP_061502321.1	None