Protein Alignment Mcm3 and Mcm7

DIOPT Version :9

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001004203.3
• Gene: Mcm7 / 288532
• RGDID: 1303018
• Length: 719
• Species: Rattus norvegicus
• Alignment Length: 706
• Identity: 232/706 - (32%)
• Similarity: 361/706 - (51%)
• Gaps: 131/706 - (18%)

  Fly     5 GEQFIKDIQRE----YVDFLDD--EED--------------QGIYAGHVKDMIAEKSKRLIVNVN 49
            |.|.:....||    ||| |||  |:|              ..::|..|::::.|..::.:||
  Rat    34 GTQLVHLAHREQVALYVD-LDDVAEDDPELVDSICENAKRYSRLFADVVQELLPEYKEKEVVN-- 95

  Fly    50 DLKRKNPQRALGLLSNAADEQLAFGRALKEYASTVDPGYAKMHEDLF---------VGFEGCFGN 105
                          .:..|..:.. |.:.|..|. |||..:..::.:         :.|:|...:
  Rat    96 --------------KDVLDVYIEH-RLMMEQRSR-DPGAVRNPQNQYPSELMRRFELYFQGPSSS 144

  Fly   106 RHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAA 170
            :....|.:.:..:|.::.|.||||:||.::|::|.:.:.|..         ....:::.:.|...
  Rat   145 KPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQ---------CGAETYQPIQSPTF 200

  Fly   171 YP----------TKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDR 225
            .|          |....|.|.....| |.:...|.:.|||..::.|.|.:|||:.:|.:.:....
  Rat   201 MPLIMCPSQECQTNRSGGRLYLQTRG-SKFIKFQEMKIQEHSDQVPVGNIPRSITVVLEGENTRI 264

  Fly   226 CKPGDRVQIVGSYRCLPGKRGGY---TSGTF-RTVLLANNISLLSK-ESNL----DISREDIMLC 281
            .:|||.|.:.|.:  ||..|.|:   ..|.. .|.|.|:.:..::| |.::    ::|.|::
  Rat   265 AQPGDHVSVTGIF--LPVLRTGFQQMAQGLLSETYLEAHRVVKMTKSEDDVSGAGELSAEEL--- 324

  Fly   282 KKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAK 346
            |::|: .|.:|.|:.|:||.|:||..||:|:|.||:|||:: .|.|.::||:|::.|:|||.|||
  Rat   325 KQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQ-SPQGMKIRGNIHICLMGDPGVAK 387

  Fly   347 SQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSD 411
            ||||.|:...|||:..|||||||||||||||..|..:||..||.||:||||:||.||||||||::
  Rat   388 SQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAE 452

  Fly   412 IDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDL 476
            .|||||||||||..::|:||||..:||||||:||||||.||||:..::..:||.|..:|||||||
  Rat   453 ADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDL 517

  Fly   477 LFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKY 541
            |:::.|..|.|.|..::.|:..:|::.....|..|||.|
  Rat   518 LWLIQDRPDRDNDLRLAQHITYVHQHSRQPPAQFEPLDM-------------------------- 556

  Fly   542 DALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQP 606
                              :.||:||.:.:..:|.:.:...:.|...|..:|.:.....|...|
  Rat   557 ------------------KLMRRYIAMCRERQPTVPDSLADYITAAYVEMRREARASKDATYT-- 601

  Fly   607 ITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVLDKDRPSKRRR 662
             :||||..::|||||.||.||...|..:|.:.||.|::.:....:.:|.:.::.:|
  Rat   602 -SARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMSKDSLLGEKGQTARTQR 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	18..101	CDD:379644	19/107 (18%)
		MCM	106..648	CDD:214631	204/560 (36%)
Mcm7	NP_001004203.3	MCM_N	12..165	CDD:291233	29/149 (19%)
		MCM	145..641	CDD:214631	204/559 (36%)
		P-loop_NTPase	376..515	CDD:304359	89/138 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820