Protein Alignment Mcm3 and mcm7

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_997734.1
• Gene: mcm7 / 192333
• ZFINID: ZDB-GENE-020419-27
• Length: 721
• Species: Danio rerio
• Alignment Length: 732
• Identity: 251/732 - (34%)
• Similarity: 359/732 - (49%)
• Gaps: 129/732 - (17%)

  Fly     5 GEQFIKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADE 69
            |.|.:....||.|..|.|.:|           :||:...|:.:|.:    |.:|...|.::|..|
Zfish    34 GAQLVSLAHREQVALLVDLDD-----------VAEEDPDLVESVCE----NAKRYTALFADAIHE 83

  Fly    70 QLAFGR--------ALKEY--------ASTVDPGYAKMHE-----DLFVGFEGCF-GNRHVTPRS 112
            .|...|        ||..|        ....||...:.|.     :|...||..| ....:.||.
Zfish    84 LLPEYREREAVVKDALDVYIEHRLMMEVRGRDPADTRDHRKQYPPELMRRFEVYFRPPATLKPRV 148

  Fly   113 LTSI---YLGNMVCVEGIVTKVSLIRPKVVRSVHYCPNT-----RKVMERKYTDL---TSFEAVP 166
            :..:   .:|.:|.|.||||:.:.::|.:..:.:.|...     :.:....:|.|   .|.|.|
Zfish   149 VRDVKADSIGQLVTVRGIVTRATEVKPMMAVATYTCDQCGAETYQPIASPSFTPLIMCPSQECV- 212

  Fly   167 SGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDR 231
                  |....|.|.....| |.:...|.|.|||..::.|.|.:|||:.|....:.....:|||.
Zfish   213 ------TNKSGGRLYLQTRG-SKFIKFQELRIQEHSDQVPVGNIPRSMTIYARGENTRVAQPGDH 270

  Fly   232 VQIVGSYRCLPGKRGGYTSGT----FRTVLLANNISLLSKESNLDISREDIMLCKKLAK--NNDI 290
            |.:.|.:  ||..|.|:....    ..|.|..::|:|::|..:.::..|::. .::|.:  ..|.
Zfish   271 VAVSGVF--LPLLRSGFRQAVQGLLSETYLECHSITLMNKTEDDELGTEELS-DEELRQITEEDF 332

  Fly   291 FELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLN 355
            :|.|:.|:||.|:||..||:|:|.||:||||: .|.|.::||:||:.|:|||.|||||||.|:..
Zfish   333 YEKLAGSIAPEIYGHEDVKKALLLLLVGGVEQ-APRGMKIRGNINICLMGDPGVAKSQLLSYIDR 396

  Fly   356 TAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEV 420
            .|||:..|||||||||||||||..|..|||..||.||:||||.||.||||||||:|.||||||||
Zfish   397 LAPRSQYTTGRGSSGVGLTAAVMRDPVTGEMTLEGGALVLADLGVCCIDEFDKMADADRTAIHEV 461

  Fly   421 MEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVID 485
            |||..::|:||||..|||||||:||||||.||||:..|:..:||.|..:||||||||:::.|..|
Zfish   462 MEQQTISIAKAGIMTSLNARCSILAAANPAYGRYNPRKSIEQNIQLPAALLSRFDLLWLIQDRPD 526

  Fly   486 SDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSR 550
            ::.|..::.|:..:|:                                            |.:..
Zfish   527 AESDLRLAQHITYVHQ--------------------------------------------HCRQP 547

  Fly   551 QRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETL 615
            ..|...:.::.||:||...|..:|.:.|...:.|...|..:|.:..|..|...|   :||||.::
Zfish   548 PTHFTPIDMKLMRRYISKCKQKQPVVPESLSDYITAAYVEMRKEARVSKDTTFT---SARTLLSI 609

  Fly   616 IRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVLDKDRPSKRRRNSGSDA-----EDDNGE- 674
            :|||||.||.||...|..:|.:.|:.|::.:  |..|..||.|..|....:|.     .:..||
Zfish   610 LRLSTALARLRMVSVVEKEDVNEAMRLMEMS--KDSLQADRSSSSRAQRPADVIFSLLRELCGES 672

  Fly   675 --------ASSQRSPSR 683
                    |:.||..||
Zfish   673 AGRSVRVSAAEQRCVSR 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	25/108 (23%)
		MCM	106..648	CDD:214631	208/558 (37%)
mcm7	NP_997734.1	MCM_N	10..103	CDD:464206	21/83 (25%)
		MCM	145..641	CDD:475121	208/556 (37%)