Protein Alignment Mcm3 and mcm3

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_997732.3
• Gene: mcm3 / 192323
• ZFINID: ZDB-GENE-020419-4
• Length: 807
• Species: Danio rerio
• Alignment Length: 833
• Identity: 505/833 - (60%)
• Similarity: 633/833 - (75%)
• Gaps: 40/833 - (4%)

  Fly     1 MAHE--GEQFIKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLL 63
            ||.|  .:|.:::.||:|:|||||::|||||...|:.||:|...|||||:|||:|:|.:||..||
Zfish     1 MAAEVVDDQEMREAQRDYLDFLDDDQDQGIYQSKVRQMISENKSRLIVNLNDLRRRNEKRAAKLL 65

  Fly    64 SNAADEQLAFGRALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPRSLTSIYLGNMVCVEGIV 128
            :||.:|.|||.||||:..:::|..|||..|:.|:|.||.||::||:||:|||..||:|||:||||
Zfish    66 NNAFEELLAFQRALKDLVASIDATYAKQCEEFFIGLEGSFGSKHVSPRTLTSRLLGSMVCLEGIV 130

  Fly   129 TKVSLIRPKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKDEDGNLLETEYGLSVYKDH 193
            ||.||:||||||||||||.|:|.||||||||||.:|.||.|.||||||:.|.||||:||||||||
Zfish   131 TKCSLVRPKVVRSVHYCPATKKTMERKYTDLTSLDAFPSSAIYPTKDEENNPLETEFGLSVYKDH 195

  Fly   194 QTLTIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLL 258
            ||:||||||||||||||||||||:.|:||||..|||||.|::|:|||||||:||:|||||||:::
Zfish   196 QTITIQEMPEKAPAGQLPRSVDIILDNDLVDAVKPGDRTQVIGTYRCLPGKKGGFTSGTFRTIMI 260

  Fly   259 ANNISLLSKESNLDISREDI----MLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGG 319
            |.::..:|||.:...|.:|:    ..|:..:||  :|:.|::|||||||||.|:|:||||:||||
Zfish   261 ACHVKQMSKEISHYFSADDVAKIKSFCRSRSKN--VFDQLARSLAPSIHGHEYIKKAILCMLLGG 323

  Fly   320 VEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETG 384
            |||:|.||:|:||||||||||||||||||||||||:|||||||||||||||||||||||||||||
Zfish   324 VEKVLENGSRIRGDINVLLIGDPSVAKSQLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETG 388

  Fly   385 ERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANP 449
            |||||||||||.|||||||||||||||:||||||||||||||||:||||||.|||||||||||||
Zfish   389 ERRLEAGAMVLGDRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANP 453

  Fly   450 VYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLS 514
            |||||||||||||||||||||||||||||:|||.:|.:.|:.|||||:||||||:|.|.||..|:
Zfish   454 VYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRDPHEQDGTALA 518

  Fly   515 MGSSYADSLSFV---SSSEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKL 576
            :|.: .|:|:..   ::.||:::.:||||::.|||| |::..::::|..|||||||:||.:.|.|
Zfish   519 LGGT-IDALATEDPDATQEEEEELQVYEKHNPLLHG-SKKNKDRVVSKAFMRKYIHVAKAISPVL 581

  Fly   577 GEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIE 641
            .:.|...||.||||||:||.:.:|:|||.|:||||||||||||||||:|||||:|.:.|...|:|
Zfish   582 TQDAANHIAEEYSRLRNQEQLGSDIARTSPVTARTLETLIRLSTAHAKARMSKAVELVDTEVAVE 646

  Fly   642 LVQFAYFKKVLDKDRPSKRRRNSGSDA-----EDDNGEASSQRSPSRRSKRTRTATVGADSDEED 701
            |||||||||||:|:|  ||.||...||     |::..||.....|.|:.:|....:...|..:.|
Zfish   647 LVQFAYFKKVLEKER--KRSRNGQQDAASEDEEEEEDEAQDTPRPPRKRRRGSQGSESYDPYDFD 709

  Fly   702 IEPPQPDAGDLTRRETRRSLPARSVAMLMASPSSEEQSVATSTTEPAIISDARLGEFKNNLQRLF 766
            .|...|        :.:...|||         ..:|:......||   :|:.|..|||..|.::|
Zfish   710 TETDIP--------QIQSPAPAR---------QGDEEPDQNGHTE---LSEDRFKEFKAALHKVF 754

  Fly   767 REAREQSLALARITTAINVGSQEPFTAGEIEAAVHRMTEDNQIMVADDIVFLI 819
            |.:..||:.|..:..:||......|...:..||:.||.:|||:|:||||:|||
Zfish   755 RSSHAQSVGLIALMESINKSCPSAFNETDFRAALARMQDDNQVMLADDIIFLI 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	48/87 (55%)
		MCM	106..648	CDD:214631	390/548 (71%)
mcm3	NP_997732.3	None