Protein Alignment Mcm3 and mcm-3

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_506706.1
• Gene: mcm-3 / 180010
• WormBaseID: WBGene00003155
• Length: 812
• Species: Caenorhabditis elegans
• Alignment Length: 835
• Identity: 416/835 - (49%)
• Similarity: 554/835 - (66%)
• Gaps: 66/835 - (7%)

  Fly    10 KDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADE----- 69
            ::|..:|::|||::.|...|...:..|:.:...||::|:::::...|:||.|||:.:..|
 Worm    19 QEITEQYLNFLDNQADTFHYRQKIVKMMNDGESRLVMNLDEIREILPERAEGLLTQSVLEMNCLQ 83

  Fly    70 ---QLAFGRALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPRSLTSIYLGNMVCVEGIVTKV 131
               |:|..|:  :..:.|..|:       .|||||.||.|||.||:|.|.||||:||.||||||.
 Worm    84 SALQMAINRS--DVQAVVKTGF-------HVGFEGTFGERHVNPRTLKSSYLGNLVCCEGIVTKC 139

  Fly   132 SLIRPKVVRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTL 196
            |.:|.|::.||||||.|.||:|:|:.|.|..:...:...|||:||:.|.||||:|.||||||||.
 Worm   140 STVRQKLLTSVHYCPATNKVLEKKFADFTMLDTAVTNNNYPTEDENKNPLETEFGHSVYKDHQTF 204

  Fly   197 TIQEMPEKAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANN 261
            ||||:||.||||||||:||.|.|.||.||.||||||:|:|.:|.||.|:.|.:||:||::::.|:
 Worm   205 TIQELPESAPAGQLPRAVDCVADLDLADRVKPGDRVRIIGVFRVLPNKQNGVSSGSFRSIIIINH 269

  Fly   262 ISLLSKESNLDISREDIMLCKKLAKNNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPN 326
            |.:||||...:...:|:...:|::|:.:.||||::||||||.||...|:|:|||||||:||||.|
 Worm   270 IQMLSKEVIPNFEPQDVKDVRKISKSRNPFELLARSLAPSICGHEETKKALLCLLLGGMEKILNN 334

  Fly   327 GTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAG 391
            |:||||||||||||||||||||||||||..|||||.||||||||||||||||||.::||||||||
 Worm   335 GSRLRGDINVLLIGDPSVAKSQLLRYVLRMAPRAITTTGRGSSGVGLTAAVTTDPDSGERRLEAG 399

  Fly   392 AMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQ 456
            ||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||:.
 Worm   400 AMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHAKLNARCSVLAAANPVYGRYNP 464

  Fly   457 YKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSYAD 521
            :|:||||||:||||||||||:||:||..|:|.|..:::||:::|.||...||||..|.||.. .:
 Worm   465 FKSPMENIGMQDSLLSRFDLIFVLLDEHDADKDANVAEHVLKLHTYRTQGEADGTVLPMGGG-VE 528

  Fly   522 SLSFVSSSEEKKDTEVYEKYDALLHGKSRQ----RHEKILSVEFMRKYIHIAKCMKPKLGEQACE 582
            ::|.::...:|..:.:||        ::.|    :..|||:::|||||||:|:.::|||.::|.|
 Worm   529 TISTINMETKKASSSIYE--------ENTQWAGIQDTKILTMDFMRKYIHLARSVQPKLTDEATE 585

  Fly   583 AIANEYSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAY 647
            .|:..|:.:||.:..:||..||.|:|||.||||||||||.|:||.||.|..:|...|..|:.||.
 Worm   586 YISEVYADIRSFDITKTDQERTMPVTARQLETLIRLSTAIAKARFSKKVEREDTEKAYNLLHFAC 650

  Fly   648 FK-KVLDKDRPSKRRRNSGSDAEDDNGEASSQRSPSRRSKRTRTATVGADSDEEDI---EPPQ-- 706
            || |...:....|::|....|.:||..:                      ||.||:   |.||
 Worm   651 FKEKPKARQEYEKKKRAPRIDGDDDEDQ----------------------SDNEDMATSEEPQSS 693

  Fly   707 --PDAGDLTRRETRRSLPARSVAMLMASPSSEEQSVA-TSTTEPAIISDARLGEFKNNLQRLFRE 768
              |.|....|...||:....|...:|.:...|.|..| .:.|.||.|...|..|.:..:::.|.:
 Worm   694 SVPTAATPRRGVRRRAEDDDSQDSMMDTTIGESQPTAKKARTGPAAIGVDRYKELRKYVRKAFDD 758

  Fly   769 --AREQSLALARITTAI--NVGSQEPFTAGEIEAAVHRMTEDNQIMVADDIVFLI 819
              :.:..:.|..||.::  ..||.: ||..|::|...::..||..|:|:|.:.||
 Worm   759 IGSTDDMVELQIITDSVQTQAGSHK-FTEDELKAGYEQLENDNAAMIAEDKITLI 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	25/95 (26%)
		MCM	106..648	CDD:214631	338/545 (62%)
mcm-3	NP_506706.1	MCM	114..649	CDD:475121	336/543 (62%)