Protein Alignment Mcm3 and Mcm3

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_032589.1
• Gene: Mcm3 / 17215
• MGIID: 101845
• Length: 812
• Species: Mus musculus
• Alignment Length: 817
• Identity: 503/817 - (61%)
• Similarity: 638/817 - (78%)
• Gaps: 22/817 - (2%)

  Fly     9 IKDIQREYVDFLDDEEDQGIYAGHVKDMIAEKSKRLIVNVNDLKRKNPQRALGLLSNAADEQLAF 73
            :::.||:|:||||||||||||...|:::|::...||||:||||:|||.:||..||:||.:|.:||
Mouse    12 LREAQRDYLDFLDDEEDQGIYQNKVRELISDNQYRLIVSVNDLRRKNEKRANRLLNNAFEELVAF 76

  Fly    74 GRALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPRSLTSIYLGNMVCVEGIVTKVSLIRPKV 138
            .||||::.:::|..|||.:|:.::|.||.||::||:||:|||.:|..:|||||||||.||:||||
Mouse    77 QRALKDFVASIDATYAKQYEEFYIGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKV 141

  Fly   139 VRSVHYCPNTRKVMERKYTDLTSFEAVPSGAAYPTKDEDGNLLETEYGLSVYKDHQTLTIQEMPE 203
            ||||||||.|:|.:||:|:|||:..|.||.:.||||||:.|.|||||||||||||||:|||||||
Mouse   142 VRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMPE 206

  Fly   204 KAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANNISLLSKE 268
            ||||||||||||::.||||||:.|||||:|:||:|||||||:|.||||||||||:|.|:..:||:
Mouse   207 KAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGCYTSGTFRTVLIACNVKQMSKD 271

  Fly   269 SNLDISREDIMLCKKLAK--NNDIFELLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLR 331
            .....|.:||...||.:|  :.|:||.|::|||||||||.|||:|||||||||||:.|.||:.:|
Mouse   272 IQPAFSADDIAKIKKFSKTRSKDVFEQLARSLAPSIHGHDYVKKAILCLLLGGVERELENGSHIR 336

  Fly   332 GDINVLLIGDPSVAKSQLLRYVLNTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLA 396
            ||||:||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||
Mouse   337 GDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLA 401

  Fly   397 DRGVVCIDEFDKMSDIDRTAIHEVMEQGRVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPM 461
            |||||||||||||||:||||||||||||||||:||||||.|||||||||||||||||||||||||
Mouse   402 DRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPM 466

  Fly   462 ENIGLQDSLLSRFDLLFVMLDVIDSDVDQMISDHVVRMHRYRNPKEADGEPLSMGSSY----ADS 522
            |||||||||||||||||:|||.:|.:.|:.|||||:|||:||.|.|.||:.|.:|||.    .|.
Mouse   467 ENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHQYRAPGEQDGDALPLGSSVDILATDD 531

  Fly   523 LSFVSSSEEKKDTEVYEKYDALLHGKSRQRHEKILSVEFMRKYIHIAKCMKPKLGEQACEAIANE 587
            ..|  :.::::||.:|||:|:|||| ::::.||::|..||:||||:||.:||.|.:::...||.|
Mouse   532 PDF--TQDDQQDTRIYEKHDSLLHG-TKKKKEKMVSAAFMKKYIHVAKIIKPTLTQESAAYIAEE 593

  Fly   588 YSRLRSQEAVETDVARTQPITARTLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVL 652
            |||||||:::.:|.|||.|:|||||||||||:||||:|||||:|.:.||..|:||||:|||||||
Mouse   594 YSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVL 658

  Fly   653 DKDRPSKRRRNSGSDAEDDNGEASSQRSPSRRSKRTRTATVGADSDEEDIEPPQPDAGDLTRRET 717
            :|::..|:.....||.||:  |..||....::.||.:|..    .|.|..:|     .|.:..||
Mouse   659 EKEKKRKKASEDESDLEDE--EEKSQEDTEQKRKRRKTHA----KDGESYDP-----YDFSEAET 712

  Fly   718 RRSLPARSVAMLMASPSSEEQSVATSTTEPAIISDARLGEFKNNLQRLFREAREQSLALARITTA 782
            :  :|.........|....:.|..|..::...:|:.||..||..|..:|:||.|||:.:..:|.:
Mouse   713 Q--MPQVHTPKTDDSQEKTDDSQETQDSQKVELSEPRLKAFKAALLEVFQEAHEQSVGMLHLTES 775

  Fly   783 INVGSQEPFTAGEIEAAVHRMTEDNQIMVADDIVFLI 819
            ||...:|||::.||:|.:.||.:|||:||::.|||||
Mouse   776 INRNREEPFSSEEIQACLSRMQDDNQVMVSEGIVFLI 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	47/87 (54%)
		MCM	106..648	CDD:214631	391/547 (71%)
Mcm3	NP_032589.1	MCM_N	16..104	CDD:464206	47/87 (54%)
		MCM	109..654	CDD:214631	394/550 (72%)
		Arginine finger	477..480		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	664..744		19/79 (24%)