Protein Alignment Mcm3 and MCMDC2

DIOPT Version :9

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_775789.3
• Gene: MCMDC2 / 157777
• HGNCID: 26368
• Length: 681
• Species: Homo sapiens
• Alignment Length: 480
• Identity: 99/480 - (20%)
• Similarity: 166/480 - (34%)
• Gaps: 136/480 - (28%)

  Fly   212 RSVDIVCDDDLVDRCKPGDRVQIVGSYRCLPGKRGGYTSGTFRTVLLANNISLLSKESNLDISRE 276
            :|:.|...|:.|::...|:..:|:|...|:.      ||.| ...:.||:|:..:.:....||
Human   229 QSLTIFLRDESVNKMNIGNEYKIIGIPTCVK------TSQT-AVCIEANSITFCNSKVPSGIS-- 284

  Fly   277 DIMLCKKLAKNNDIFE---LLSKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLL 338
            |...|.....::..::   :|:...|..|..........||||:..|:....| ..|...:::|:
Human   285 DNFRCLLSLTSSSCWKFTAILANIFASQITPPGTYNLLKLCLLMSLVQTTDRN-KELEDCLDILI 348

  Fly   339 IGDPSVAKSQLLRYVLNTAPRAI---------PTTGRGSSGVGLTAAVTTDQETGERRLEAGAMV 394
            |...::...:||.:.:|..||.|         ||..|...|            ||...::||:.:
Human   349 ITSDTLLIDRLLNFSINLVPRGIRHLVSTEIFPTLSRNKYG------------TGAVSIQAGSAL 401

  Fly   395 LADRGVVCIDEF-----DKMSDIDRTAIHEVMEQGRVTISKAG--------IHASLNARCSVLA- 445
            ||..|:..|.:.     ||:..     :..|:|...:|:...|        ...:...:||..:
Human   402 LAKGGICFIGDLASHKKDKLEQ-----LQTVLESRSITVYIPGKKFGEDIDQQMTFPVQCSFWSF 461

  Fly   446 ------------AANPVYGRYDQYKTPMENIGLQDSLLSRFDLLF---------VMLDVIDSDVD 489
                        ..|.:.|:.|....|.       :|:..|.||.         ..|..:...::
Human   462 VDVDSSSRRNAQKINTLIGQMDCSLIPA-------NLVEAFGLLINCNESSPCHPFLPTVQHTLN 519

  Fly   490 QMISDHVVRMHRYRNPKEADGEPLSMGSSYADSLSFVSSSEEKKDTEVYEKYDALLHGKSRQRHE 554
            :.|           ||:         |..||.|..|.        ||.:||..|.         .
Human   520 KAI-----------NPE---------GLFYAASRQFT--------TEDFEKLLAF---------A 547

  Fly   555 KILSVEFMRKYIHIAKCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITARTLETLIRLS 619
            |.|:|||                  :.||....:....:...:.|.......::|..|:.|:.||
Human   548 KNLNVEF------------------SLEAERMTHGYYLASRRIRTGSVCGSKLSASALKYLVFLS 594

  Fly   620 TAHARARMSKSVTIDDAHAAIELVQ 644
            .||||..:...|..:|...|..|.:
Human   595 EAHARLNLRNKVLKEDVLIAALLFE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	18..101	CDD:379644
		MCM	106..648	CDD:214631	99/480 (21%)
MCMDC2	NP_775789.3	PTZ00111	<358..>435	CDD:173403	22/93 (24%)
		MCM	<514..622	CDD:278895	34/161 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810