Protein Alignment Mcm3 and LOC1273388

DIOPT Version :10

• Sequence 1: NP_511048.2
• Gene: Mcm3 / 31449
• FlyBaseID: FBgn0284442
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_312356.3
• Gene: LOC1273388 / 1273388
• VectorBaseID: AGAMI1_009590
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 743
• Identity: 218/743 - (29%)
• Similarity: 349/743 - (46%)
• Gaps: 128/743 - (17%)

  Fly     9 IKDIQREYVDFLDDEEDQGIYAG---HVKDMIAEKSKRLIVNVNDLKR---KNPQRALGLLSNAA 67
            ::.:|:.|.||.|..:...:.|.   .:|....:..::|....:.|::   .:|:..|..:..|.
Mosquito   115 VRAMQKHYSDFADLYDLPQVKATCWFELKLDACDNDQQLRTQWSTLRQDLMDSPEHTLACIGLAM 179

  Fly    68 DEQLAFGRALKEYASTVDPGYAKMHEDLFVGFEGCFGNRHVTPR--------SLTSI---YLGNM 121
            ...|     :.:..:......||:          |.  :.:.||        |::||   .:|.:
Mosquito   180 HHTL-----MSQQPTGSTQSDAKL----------CL--QTIRPRIVGYGPEVSISSIKVSSMGKL 227

  Fly   122 VCVEGIVTKVSLIRPKVVRSVH--------YCPNTRKVMERK--YTDLTSFEAVPSGAAYPTKDE 176
            |.|.|     ::||....:.::        .|.:.:.|.::.  ||..||..   ||.    |..
Mosquito   228 VSVRG-----TIIRAGATQIMNTWCAFRCAQCGSEQAVQQKDGIYTTPTSCH---SGC----KAR 280

  Fly   177 DGNLLETEYGLSVYKDHQTLTIQEMPE--KAPAGQLPRSVDIVCDDDLVDRCKPGDRVQIVG--S 237
            ...:|..:...:..:.:|||.:||..:  :..||...::::|....:|||...|||.|.:.|  .
Mosquito   281 SHFVLLQQSAFTRMEAYQTLRLQETTQGSRTVAGSAAKNIEIELTHELVDSVCPGDDVTVTGILK 345

  Fly   238 YRCLPGKRGGYTSGTFRTVLLA----NNISLLSKESNL----DISREDIMLCKKLAKNNDIFELL 294
            .|...|..|...:..|:..|.|    :|.::|:..:.|    ::..|.|.|.|   .....|.||
Mosquito   346 ARSQDGSDGAGKASMFKAYLQAVYVRSNKNVLANWNRLAEFTELDMEAIRLIK---AEPSPFRLL 407

  Fly   295 SKSLAPSIHGHAYVKQAILCLLLGGVEKILPNGTRLRGDINVLLIGDPSVAKSQLLRYVLNTAPR 359
            .:||.|:|:||..||..:|..|.||    :.|..|.|.:|:||::|||.:.|||:|:...|.:||
Mosquito   408 VQSLCPTIYGHEIVKAGLLLGLFGG----MANTARTRAEIHVLVVGDPGIGKSQILQSCANVSPR 468

  Fly   360 AIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRTAIHEVMEQG 424
            .|...|..||.||||..|.|::..| ..|||||:||||:||.|||||||||  ..:.:.|||||.
Mosquito   469 GIFVCGTNSSNVGLTVTVRTEKGVG-ASLEAGALVLADQGVCCIDEFDKMS--GHSGLLEVMEQR 530

  Fly   425 RVTISKAGIHASLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFVMLDVIDSDVD 489
            .|:::|||:..::.||.:|||||||..|.|::.||..||:.|..:|||||||:|::||..:...|
Mosquito   531 SVSVAKAGVICTVPARTTVLAAANPAGGHYNKAKTVSENLKLHPALLSRFDLVFILLDRSNERTD 595

  Fly   490 QMISDHVVRMHRYRNPKEADGEPLSMGSSYAD---SLSFVSSS-----EEKKDTEVYEKYDALLH 546
            .:::.|:.::|..          ...|||:..   |..|..:|     ||:.:..:.|:. .|..
Mosquito   596 NLLTAHIQKVHGL----------AKAGSSHLQPQPSHPFFDASGHCSYEEEGEPPLEERL-RLAP 649

  Fly   547 GKSRQRHEKILSVEFMRKYIHIA-KCMKPKLGEQACEAIANEYSRLRSQEAVETDVARTQPITAR 610
            |:...    :|..|.::|||..| |.::|||..:|.|.:...:..||.... ..|:.   |:|.|
Mosquito   650 GEQMD----LLPPEIVQKYIGYARKNVQPKLTAKAAEELREFFVELRRAHN-HMDMI---PVTTR 706

  Fly   611 TLETLIRLSTAHARARMSKSVTIDDAHAAIELVQFAYFKKVLDKDRPSKRRRNSGSDAED----- 670
            .||.||||:.|.|:..:|...|:......:.:::    :.:||.         ..:|..|
Mosquito   707 QLEGLIRLTQARAKIDLSPEATVAHVRDVLAILR----QSMLDV---------FSTDEGDLQFTR 758

  Fly   671 -DNGEASSQRSPSRRSKR---TRTATVG 694
             .||..:|:.|..|:..|   :|:|..|
Mosquito   759 LTNGSGTSKTSMVRKFARVLASRSAVTG 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm3	NP_511048.2	MCM_N	13..101	CDD:464206	15/93 (16%)
		MCM	106..648	CDD:214631	189/583 (32%)
LOC1273388	XP_312356.3	Mcm2	224..832	CDD:440854	197/617 (32%)