DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnp4F and NOP13

DIOPT Version :9

Sequence 1:	NP_001096883.3	Gene:	Rnp4F / 31448	FlyBaseID:	FBgn0014024	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_014224.2	Gene:	NOP13 / 855547	SGDID:	S000005119	Length:	403	Species:	Saccharomyces cerevisiae

Alignment Length:	359	Identity:	67/359 - (18%)
Similarity:	124/359 - (34%)	Gaps:	104/359 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   617 QALDLPVEYVKPRSRIKPNSQSAYPRQQKLKPRQQQQQTNREPLNR---------EQRRRQAHEQ 672
            :||..|.:..|....|:.:.:|:.|..:|.|...::.:...|.||.         |:.:..|.::
Yeast    23 KALLDPTKKRKAEDEIEIDLKSSIPLSKKQKRLLRRGKVTLEELNAKYNIDPKSIEEYKEDAEKK 87

  Fly   673 QQQQQQQQKHGIKKSRTEPSGGATSPPSKVKGPANAEAKESNFKYSPNMEINKIFVRNLHPACSK 737
            :....::...|.:.:...|:|..:....|.|       |:...||.       :::.||....:|
Yeast    88 KSGASEKDAQGEESTINTPTGDESGEVVKKK-------KKDENKYG-------VWIGNLSFDTTK 138

  Fly   738 EELHELFSPFGTIKD------------------VRLVHKLNKQF--KGIAYVEFEKPGEAQRAVA 782
            ::|...|  ....||                  .|:..|.:...  ||..|: |.|..|..:||.
Yeast   139 DDLVRFF--IAKTKDNEDEKSRVTEQDITRLSMPRVAAKNSNAMKNKGFCYM-FFKNVEQMKAVL 200

  Fly   783 GRDGCLFKGMNISVAISNPPPRGTSAVKPS----VAPKRRVPTSLIPTTLVRQEVAAKKLRLLLP 843
            ........|.|:.:..|.     ..:.:|.    ||..:..|:.::....:..:|....||....
Yeast   201 ELSESHLNGRNMLIKDSE-----NYSGRPDKDDLVAMSKNPPSRILFVGNLSFDVTDDLLRKHFQ 260

  Fly   844 EPGDI--------------------------SSTSASVDVAIKREAN-------GEEQ-KGDVQE 874
            ..|||                          .||:|..|.:.::.|.       ||:: |..|::
Yeast   261 HCGDIVKIRMATFEDSGKCKGFAFIDFKNEEGSTNALKDKSCRKIAGRPLRMEYGEDRSKRQVRK 325

  Fly   875 RDE--------------QKGEEQKGEEQKGEEPK 894
            :.|              .||.::.|:: .|.:|:
Yeast   326 KVENVSRNNSSSFDISNNKGYDRAGQD-NGSKPE 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnp4F	NP_001096883.3	RRM	<681..>811	CDD:223796	28/149 (19%)
		RRM_SF	722..802	CDD:302621	20/99 (20%)
		Paf1	<816..922	CDD:281915	22/127 (17%)
		Lsm_interact	922..940	CDD:283133
NOP13	NP_014224.2	RRM1_Nop13p_fungi	127..217	CDD:409830	19/92 (21%)
NOP13	NP_014224.2	RRM2_Nop13p_fungi	241..316	CDD:409831	11/74 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3656
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030