Protein Alignment Rnp4F and ncl

DIOPT Version :9

• Sequence 1: NP_001096883.3
• Gene: Rnp4F / 31448
• FlyBaseID: FBgn0014024
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_001070120.2
• Gene: ncl / 767714
• ZFINID: ZDB-GENE-030131-6986
• Length: 705
• Species: Danio rerio
• Alignment Length: 864
• Identity: 148/864 - (17%)
• Similarity: 255/864 - (29%)
• Gaps: 320/864 - (37%)

  Fly     9 RQLEKELDEMPAEDLDDDAYDEYDLIVIPDQGKGSP----QQGHSESPQQEEEHKSEELRQRSRP 69
            :::|:|..|   ||.|||..:|...:....:...:|    :.|.:.:.|:.|:...::....|..
Zfish    23 KEVEEESSE---EDSDDDEEEEAPPVKAVAKKNAAPVKAVKNGKAAAKQESEDEDDDDEDDESEE 84

  Fly    70 TWPP----------------SSAGGDMTTIELISSDDEPSVEE-----------------TEGGN 101
            ..||                .:|..:.::.|....||:...||                 |....
Zfish    85 EAPPPKKAAKAPAKAAAPAKKAAPAEESSEEDDDDDDDDESEEEAPPPKKAPAKATPAKATPAKK 149

  Fly   102 AAGRGRARNDSSSSSDDVGVIEGSELES---------------------NSEVSSDSDSDSDNAG 145
            ||...:|.....|..||....|..|.|:                     .|:...|.|.:.|::
Zfish   150 AAPVKKAAPAEESEDDDDDEDESEEEEAPPPKKAAAAAKPAAKAPAAKEESDEEEDDDEEEDDS- 213

  Fly   146 GGNQLERSYQELNALPSKKFAQMVSLIGIAFKLNDLEKIESSVLELQNLATVPAHVWLKYLKARL 210
                 |....:....|..|.|.||.....:.:.:|.::.:....|.:.....||       |.:
Zfish   214 -----EEEEMDTTPAPKAKKAGMVKAKEESEEEDDDDEEDDDDEEEEETPATPA-------KRK- 265

  Fly   211 VVTQTDEERKAFEEQCAKALGYYYSIPLSEYVVNYLVDQGNVQNHVLWAKLLADYDVERPDFGDK 275
              .:|.:|:.....:.||..|..:|:.|           ||:.|:              .||
Zfish   266 --AETKKEKGTPPAKKAKTDGEGFSLFL-----------GNLNNN--------------KDF--- 300

  Fly   276 LRSLISTITDENEAAAFVEMLQKHCVTWTCNVEQRQMIKSVVDKFKQHLDETTRGWDWSEQHKAH 340
                     ||                          :||.:.||
Zfish   301 ---------DE--------------------------LKSAISKF-------------------- 310

  Fly   341 VYDVETLSLDDDLKNAVIRFIFERSVAKFPIVDVLWLSYIEFIQFEGVTVPENEDENEVTAEMVA 405
             :..|.|.:.|.......:|                 .|::|         .:|:|.:...|:..
Zfish   311 -FSKEGLEIQDVRLGGTKKF-----------------GYVDF---------ASEEELQKALELNG 348

  Fly   406 KRAKRLGKGFLRNTELDLANRGVRSHPSVQLNHRFLD----LMERSDFELAEVDEEIRLILQRIV 466
            |  |.||    :..:||.|    ||..:.|.|.:..|    .::...:.:.:.|      |:.|
Zfish   349 K--KLLG----QPVKLDKA----RSKENSQENKKERDARTLFVKNLPYSITQDD------LREI- 396

  Fly   467 TDMDMTVELHLDYLAYRIRNTNASDEQQVASL----RAAFNHAWEELTVLYGDQADTRYEVLQLW 527
              .|..|::       |:...|....:.:|.:    .|....|.||   ..|.....|..:
Zfish   397 --FDQAVDI-------RVPMGNTGTSRGIAYIEFKTEAIAEKALEE---AQGSDVQGRSII---- 445

  Fly   528 AQVEYTQLGSPDNGREIWRQIMGYPGSSIRGLLWLNFAQMESEYNGGHGTRDVLRKALSQPVLEN 592
              |::|...|...||       |.|.:| :.|:..|.|...||    ...:.|..||:|..:.:|
Zfish   446 --VDFTGDKSRQGGR-------GAPSAS-KVLVVNNLAFSASE----DSLQSVFEKAVSIRIPQN 496

  Fly   593 GLMVQEF-FRRYERCYGTYESIAACQALDLPVEYVKPRSRIKPNSQSAYPRQQKLKPRQQQQQTN 656
            ....:.: |..:|....:.|::..|...|:....:                      |.:..|.:
Zfish   497 NGRPKGYAFVEFENVEDSKEALENCNNTDIEGRSI----------------------RLEYSQND 539

  Fly   657 REPLNREQRRRQAHEQQQQQQQQQKHGIKKSRTEPSGGATSPPSKVKGPANAEAKESNFKYSPNM 721
            ||                      :.|        .|...|.|:|.
Zfish   540 RE----------------------RGG--------GGRGNSGPTKT------------------- 555

  Fly   722 EINKIFVRNLHPACSKEELHELFSPFGTIKDVRLVHKLNKQFKGIAYVEFEKPGEAQRAVAGRDG 786
                :||:.|....:.:.|.:.|.  |.|.......:.....||..:|:|:...:.:.|....|.
Zfish   556 ----LFVKGLSDDTTDQTLKDSFD--GAIAARIATDRDTGSSKGFGFVDFDNEQDCKAAKEAMDD 614

  Fly   787 CLFKGMNISVAISNPPPRG 805
            ....|..:::..:.|...|
Zfish   615 GEIDGNKVTLDYAKPKGEG 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnp4F	NP_001096883.3	RRM	<681..>811	CDD:223796	21/125 (17%)
		RRM_SF	722..802	CDD:302621	14/79 (18%)
		Paf1	<816..922	CDD:281915
		Lsm_interact	922..940	CDD:283133
ncl	NP_001070120.2	RRM1_NCL	287..361	CDD:240849	28/189 (15%)
		RRM	347..630	CDD:223796	72/406 (18%)
		RRM2_NCL	374..450	CDD:240850	16/100 (16%)
		RRM3_NCL	464..535	CDD:240851	17/97 (18%)
		RRM4_NCL	554..631	CDD:240852	16/101 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910