Protein Alignment Sas10 and SAS10

DIOPT Version :9

• Sequence 1: NP_572215.1
• Gene: Sas10 / 31447
• FlyBaseID: FBgn0029755
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_010128.1
• Gene: SAS10 / 851403
• SGDID: S000002312
• Length: 610
• Species: Saccharomyces cerevisiae
• Alignment Length: 621
• Identity: 137/621 - (22%)
• Similarity: 222/621 - (35%)
• Gaps: 237/621 - (38%)

  Fly     6 DDY------VMSGSDQEYD---DEEREILEDLRKQRKKPHDPVQEVLGFSDDDD--DDDDDDEEE 59
            ||:      |:.|.....|   |::..:|||         :..:|||...:||:  |:.:|:|||
Yeast    27 DDFASKREKVLLGQSTFGDSNKDDDHSLLED---------EDEEEVLAMDEDDESIDEREDEEEE 82

  Fly    60 QQDVAELMRDSDIEGA-----------------EDDDRD--LPNTMDWGSKRSTYYNTDFVDQDY 105
            :::        :::||                 |:|:.:  |.|...|||.:..||..|.:|.|
Yeast    83 EEE--------ELDGAAAYKKIFGRNLETDQLPEEDEENGMLDNENAWGSTKGEYYGADDLDDD- 138

  Fly   106 SSYNAQEEEQARAEEEEAKKIQLRLAKRMSEADFQLDNVE----AAPAGSSDDNELSHITKVT-- 164
                    |.|:..|:||.:.|.:..:.::..|: ||..|    ...|...|..|..:.||..
Yeast   139 --------EAAKEIEKEALRQQKKHLEELNMNDY-LDEEEEEEWVKSAKEFDMGEFKNSTKQADT 194

  Fly   165 ----SDLAGLSERERRQLMHSESPEFIILTQDFQQHLDEVKNLLKPVLNYVRKHDVPMVPALQYA 225
                :|:..:.:..|...:.:..|||..|:::|.:...:...|.|...|...|  :.::....|.
Yeast   195 KTSITDILNMDDEARDNYLRTMFPEFAPLSKEFTELAPKFDELKKSEENEFNK--LKLIALGSYL 257

  Fly   226 GLCHTVLTTYCSNVAFYLLLKARRIDVKAHPVIRRLVQLKDL----------------------- 267
            |    .::.|.|.:...|........:|.|||:.:::..|::
Yeast   258 G----TISCYYSILLHELHNNEDFTSMKGHPVMEKILTTKEIWRQASELPSSFDVNEGDGSESEE 318

  Fly   268 -----------IEELK-----------------------------------PRYEEYI------- 279
                       :.||:                                   ..:|||:
Yeast   319 TANIEAFNEKKLNELQNSEDSDAEDGGKQKQEIDEEERESDEEEEEEDVDIDDFEEYVAQSRLHS 383

  Fly   280 RPQLEALLERIEDGDAFTVLDVA-----QRKAKLQILNKYND--GQQASVSSDDDDNDDD----- 332
            :|:..::.|    .|.|...::|     .:||:.:.|..|..  .||.:..:|....|||
Yeast   384 KPKTSSMPE----ADDFIESEIADVDAQDKKARRRTLRFYTSKIDQQENKKTDRFKGDDDIPYKE 444

  Fly   333 -----------------------DDAESKEKDLQEEA--------GE------------------ 348
                                   .|.:.|:...::||        ||
Yeast   445 RLFERQQRLLDEARKRGMHDNNGADLDDKDYGSEDEAVSRSINTQGENDYYQQVQRGKQDKKISR 509

  Fly   349 --------------------EEEEEDARRGITYQMAKNKGLTPHRKKELRNPRVKHRGKYRKALI 393
                                |....|.:|.|.||:.|||||||.|.|:.||.|||.|.||:||..
Yeast   510 KEAHKNAVIAAREGKLAELAENVSGDGKRAINYQILKNKGLTPKRNKDNRNSRVKKRKKYQKAQK 574

  Fly   394 RRKGAVRTVRKELQR--YGGELSGIKAGVTKSVKFR 427
            :.| :||.|....|.  |.||.:|||.|:|:||||:
Yeast   575 KLK-SVRAVYSGGQSGVYEGEKTGIKKGLTRSVKFK 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sas10	NP_572215.1	Sas10_Utp3	191..269	CDD:281929	15/111 (14%)
		Sas10	354..426	CDD:286457	39/73 (53%)
SAS10	NP_010128.1	Sas10_Utp3	220..296	CDD:397897	17/81 (21%)
		Sas10	534..608	CDD:401352	39/74 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345827
Domainoid	1	1.000	70	1.000	Domainoid score	I2278
eggNOG	1	0.900	-	-		E1_KOG3118
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	76	1.000	Inparanoid score	I1651
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004426
OrthoInspector	1	1.000	-	-		oto99924
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13237
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1729
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.970