DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sas10 and utp3

DIOPT Version :9

Sequence 1:	NP_572215.1	Gene:	Sas10 / 31447	FlyBaseID:	FBgn0029755	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_012826980.1	Gene:	utp3 / 100145025	XenbaseID:	XB-GENE-989352	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	161/442 - (36%)
Similarity:	235/442 - (53%)	Gaps:	67/442 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SDQEYDDEEREILEDLRKQRKKPHDPVQEVLGFSDDDDDDDDDDEEEQQDVAELMRDSDIEGAED 77
            ||:|..|.|.|::.                |...::|:||||.|:...        :||:|...:
Frog    99 SDEEQMDSEDEVMP----------------LDIHEEDEDDDDGDQSSM--------ESDLEERRN 139

  Fly    78 DDRDLPNTMDWGSKRSTYYNTDFVDQDYSSYNAQEEE---QARAEEEEAKKIQLRLAKRMSEADF 139
            |  .||:.|.||.::..||:||:.:.........:||   :|..|||||:.||.|||..::|.|:
Frog   140 D--GLPDEMAWGQRKKIYYDTDYAEYSTKKVKKSKEEIDAEAEEEEEEAQNIQRRLAITLNEEDY 202

  Fly   140 QLDNVEAAPAGSSDDNELSHITKVTSDLAGLSERERRQLMHSESPEFIILTQDFQQHLDEVKNLL 204
            .||.::  ..|.....|.....|:..||..:||:|:|:|:..||||.:.|.||.:..|.||||.|
Frog   203 GLDFIQ--EFGEKQSEEKQSEQKIVKDLNKMSEKEKRKLLKKESPELLELMQDLKLKLAEVKNEL 265

  Fly   205 KPVLNYVRKHDVPMVPALQYAGLCHTVLTTYCSNVAFYLLLKARRIDVKAHPVIRRLVQLKDLIE 269
            :|:|..|:...:|......|....:.:...||:|:::||:|||:||.:..||||.|||..::||.
Frog   266 EPLLKLVKNGTIPKGKGSTYLQTKYQLYLNYCTNISYYLILKAKRISIHGHPVIERLVTYRNLIN 330

  Fly   270 ELKPRYEEYIRPQLEALLERIEDGDAFTVLDVAQRKA--------KLQILNKYNDGQQASVSSDD 326
            :|. ..::.:..:::.||.:     .|...:|.|:.:        |........|.|.      |
Frog   331 DLN-IVDQRLSSEIKQLLTQ-----DFNETEVGQKNSSSLPKTSKKAATKRPLPDIQY------D 383

  Fly   327 DDNDDDDDAESK----------------EKDLQEEAGEEEEEEDARRGITYQMAKNKGLTPHRKK 375
            :|:|.|::...|                |::|..:...||.:.:|:|.||||:||||||||.|||
Frog   384 EDSDLDEEVALKYYKEMEQKLLEKRNRGEENLVTDLPSEELDPNAKRAITYQIAKNKGLTPKRKK 448

  Fly   376 ELRNPRVKHRGKYRKALIRRKGAVRTVRKELQRYGGELSGIKAGVTKSVKFR 427
            ..||||||||.|:|:|.|||||.||.||||..||.||||||:|||.||:|.:
Frog   449 LDRNPRVKHREKFRRAKIRRKGQVREVRKEEARYSGELSGIRAGVKKSIKLK 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sas10	NP_572215.1	Sas10_Utp3	191..269	CDD:281929	31/77 (40%)
Sas10	NP_572215.1	Sas10	354..426	CDD:286457	52/71 (73%)
utp3	XP_012826980.1	Sas10_Utp3	252..330	CDD:367765	31/77 (40%)
utp3	XP_012826980.1	Sas10	429..499	CDD:370454	51/69 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I6519
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3135
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1451774at2759
OrthoFinder	1	1.000	-	-		FOG0004426
OrthoInspector	1	1.000	-	-		oto104479
Panther	1	1.100	-	-	LDO	PTHR13237
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6319
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070