DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15930 and tdrd5

DIOPT Version :9

Sequence 1:	NP_572214.2	Gene:	CG15930 / 31446	FlyBaseID:	FBgn0029754	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	XP_031756124.1	Gene:	tdrd5 / 780220	XenbaseID:	XB-GENE-5884032	Length:	1010	Species:	Xenopus tropicalis

Alignment Length:	533	Identity:	97/533 - (18%)
Similarity:	188/533 - (35%)	Gaps:	139/533 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 TLLSKLRKISEEAEDNNDVPLDLRCPSAKMRNNKVLADLSDMLKVVE-DIALEEKTTDS------ 71
            ::|..||.|::..|..     ..|..|..:..|.....:|..|.|.: .:|::.|.|..
Frog   216 SMLEVLRSITDIVEVK-----QTRAGSLLVLRNSETGRISASLCVKQSQLAIDPKKTSCVLEQCL 275

  Fly    72 KKPANSEQQINGTIELALDLRQPNAKIRL--------------VISDSSDLQKVFEKAHIALE-- 120
            |:|...|::.:.|:.. |.:..|..: :|              :|:.|:..|::  |.::.|:
Frog   276 KEPRTPEKKTSETVTY-LKVSPPEPQ-KLSSKESPSVTRSTSPLINSSNKEQRL--KLNVLLDES 336

  Fly   121 LKTTDSKPTAETDDQHHVRIFDKMLCNIVV----------------------------PPDVADV 157
            ||:.::|....|:....|...:.:|.|.:|                            .||.:.:
Frog   337 LKSNENKAPPVTNFTSAVPSHNSVLSNSLVGNSVSSETLFTKMSRPTSHVEADHSAASEPDASVL 401

  Fly   158 QVNGKPLEQLL----------ATVSERQAMN-------NPGPMKMHELHTGNADFMNSNSQVAEA 205
            :...|.||:.|          .:||:...|:       :...:|:.:|.|....|...:....|.
Frog   402 EWLEKKLEKELKLCLARKGAGGSVSDALRMDIQHVVNQHSDGLKISQLPTVFKSFTGKDLPFKEL 466

  Fly   206 A-ASVETLLASTSD---NDSDSDGLESKTTDGYIVKELIPSFSDFPDIGDVSLCALMYG------ 260
            . .||..|:.|..|   .:|..||.:.|..|.. .|:|:..||    .|..|..:::..
Frog   467 GFISVMELVGSLGDILCVESTVDGKDWKLFDAK-KKDLVDEFS----AGLPSTSSILSSWNSSQQ 526

  Fly   261 --LPMDAVG---------MHW-------------KLPPQRIQD-------ICKEDSIFPIIMSCV 294
              .|:..||         :.|             .:||..:::       ..|...:..:.:..:
Frog   527 TTTPVKPVGTIFSKVDEKLWWGPLELKLCSTEQIDIPPDAVRNQKLHCLPSMKRGFMIGVYVENI 591

  Fly   295 FSPCEFWFHIVPPQYAKNPVAEMTIDLNWFYRHTTISSYRAELPSYFYKEG-------YICAAYS 352
            .||.:|:........::. :.:|.|::...|.:..:|.      .|...:.       |......
Frog   592 ESPSQFYVRCCGKDTSEK-LEDMMIEMRHCYSNECVSE------RYIVTDNCISVGQIYALRVPG 649

  Fly   353 ECGWRRAMVLVTAPLDAQCVNIEYVDHALSVTLAPNHLRFLPLSFARTPPLVFRGKMSHVRPLAN 417
            :..|.|  |:|....:::.:::.|.|.....|:..:.||||...:.:.|.......:.:|....:
Frog   650 DVWWYR--VIVHDIKNSELLDVFYPDFGNVATVKKSWLRFLKNCYMKIPAQAVPSSLPYVTSTED 712

  Fly   418 GWPKNGITAFQRM 430
            .|....|..||::
Frog   713 QWSAQAIKKFQQL 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15930	NP_572214.2	TUDOR	281..411	CDD:278965	22/136 (16%)
tdrd5	XP_031756124.1	LOTUS_1_TDRD5	50..142	CDD:193599
		LOTUS_2_TDRD5	174..242	CDD:193589	7/30 (23%)
		LOTUS_3_TDRD5	426..499	CDD:193590	17/72 (24%)
		Tudor_TDRD5	587..704	CDD:410490	21/125 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910