Protein Alignment TrxT and TXN

DIOPT Version :10

• Sequence 1: NP_572212.1
• Gene: TrxT / 31443
• FlyBaseID: FBgn0029752
• Length: 157
• Species: Drosophila melanogaster
• Sequence 2: NP_003320.2
• Gene: TXN / 7295
• HGNCID: 12435
• Length: 105
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 78/382 - (20%)
• Similarity: 121/382 - (31%)
• Gaps: 146/382 - (38%)

  Fly    76 TGNLAVDPKFIGEAGQGILSIENTSAESLKIFSRLAQAMKSDGALAIAQTNHIGVQAQTAYTNSL 140
            |..:|..|.|:...|.       ..||.|           .||.:..|              |.|
Human   346 TKKVASFPSFVAVPGP-------CEAEDL-----------IDGIIFAA--------------NYL 378

  Fly   141 GEQHILVKEVANP-MNFSVQQIKENV--LKRFANAASVLYESGFDG---------MEIHSAHGMI 193
            |...:|.:.  || .|..:.|.:|.|  :||...||.:..::..:|         :.|.:....:
Human   379 GSTQLLSER--NPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKV 441

  Fly   194 FN----QFLAPKNTRNDEYGGSIENRARLLTETYKAVREVVPESTGFIVGVKLNSRDFQESGISR 254
            .|    :.:.....|...|...|.|...|:      .|..:|.|.         |:|..|:....
Human   442 LNADTQETMMDHALRTISYIADIGNIVVLM------ARRRMPRSA---------SQDCIETTPGA 491

  Fly   255 EDIIK----VCELIENSGFDFVELTGGAMESVVKE-------------VQKRHSTI--AREDFFL 300
            ::..|    :|.:.|:.....:..:.|...||..:             .||.:|.|  .:|.:..
Human   492 QEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYND 556

  Fly   301 DFVQFT-SKIFKET-----------VVYITGRWQT-------ANAM----------------VTS 330
            |.:.|: |:..||.           ||.:...|.:       ||.|                :.|
Human   557 DLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMS 621

  Fly   331 VNMGLTSGVGLGRWSCSEPDFPRKLIAG---------EIFSC----------PDLKF 368
            :|.  ||.|||...:|      :.:|.|         .|.||          ||||:
Human   622 ING--TSLVGLPLATC------QGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKY 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TrxT	NP_572212.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	14..106	CDD:469754	8/29 (28%)
TXN	NP_003320.2	TRX_family	11..102	CDD:239245