DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TrxT and Y49E10.4

DIOPT Version :9

Sequence 1:	NP_001284881.1	Gene:	TrxT / 31443	FlyBaseID:	FBgn0029752	Length:	157	Species:	Drosophila melanogaster
Sequence 2:	NP_499613.1	Gene:	Y49E10.4 / 176664	WormBaseID:	WBGene00013030	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	145	Identity:	32/145 - (22%)
Similarity:	61/145 - (42%)	Gaps:	18/145 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RNKDDLDQQLILAE---DKLV-------VIDFYADWCGPCKIIAPKLDELAQQYSDRVVVLKVNV 60
            :..|...:.::|.:   ||||       :::|:|.|||.|:.:.|:..:.|::...||....::.
Worm   148 KKSDKKGKVVVLTDSNFDKLVLNSKEPWMVEFFAPWCGHCQKLEPEWKKAAEEMGGRVKFGALDA 212

  Fly    61 DENEDITVEYNVNSMPTFVFIKGG-----NVLELFVGCNSDKLAKLMEKHAGVYTDEAADVKAVH 120
            ..:|.|..::.:...||..|...|     :..:...|..|..|....|..   |.|..|..:.|.
Worm   213 TAHESIAQKFGIRGFPTIKFFAPGTSSASDAEDYQGGRTSTDLISYAESK---YDDFGAAPEVVE 274

  Fly   121 IDGECIVDLTAESSE 135
            ..|:.:|:...:..:
Worm   275 GTGKAVVETVCKDKQ 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TrxT	NP_001284881.1	Thioredoxin	13..105	CDD:278513	25/106 (24%)
Y49E10.4	NP_499613.1	PDI_a_P5	26..127	CDD:239299
		PDI_a_P5	156..259	CDD:239299	24/102 (24%)
		P5_C	269..405	CDD:239281	3/21 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910