DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment snf and rnp-2

DIOPT Version :9

Sequence 1:	NP_511045.1	Gene:	snf / 31442	FlyBaseID:	FBgn0003449	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_500504.1	Gene:	rnp-2 / 177181	WormBaseID:	WBGene00004385	Length:	206	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	108/216 - (50%)
Similarity:	144/216 - (66%)	Gaps:	13/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EMLPNQTIYINNLNEKIKKEELKKSLYAIFSQFGQILDIVALKTLKMRGQAFVIFKEIGSASNAL 66
            |:.||.|:||||||||||.:||:|||.|:|.|||:|:.::..:||||||||.|||||:.:||.|.
Worm     3 EVAPNSTLYINNLNEKIKIDELRKSLVAVFKQFGEIVSVMCFRTLKMRGQAHVIFKELPAASAAR 67

  Fly    67 RTMQGFPFYDKPMQIAYSKSDSDIVAKIKGTF-KERPKKVKPPKPAPGTDEKKDKKKKPSSAENS 130
            ..:.|||||:|||:|.:::.|||:||:.|||: |..||.:         .||..||.|....||.
Worm    68 EALNGFPFYEKPMRIQFAREDSDVVAQEKGTYIKREPKYL---------SEKILKKPKSRKKENG 123

  Fly   131 NPNAQTEQPPNQILFLTNLPEETNEMMLSMLFNQFPGFKEVRLVPNRHDIAFVEFTTELQSNAAK 195
            ...   ..|||:|||.||||:.....||.::||||.|.|::|:||||..||||||.|:..:..|:
Worm   124 GDG---PAPPNKILFCTNLPDSATAEMLEIMFNQFAGLKDIRMVPNRPGIAFVEFDTDSLAIPAR 185

  Fly   196 EALQGFKITPTHAMKITFAKK 216
            ..|..|||:..|.|::.:|||
Worm   186 TTLNNFKISAEHTMRVDYAKK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snf	NP_511045.1	RRM	<5..177	CDD:223796	88/172 (51%)
		RRM_SF	6..96	CDD:302621	53/89 (60%)
		RRM2_SNF	137..216	CDD:240923	38/78 (49%)
rnp-2	NP_500504.1	RRM	<6..206	CDD:223796	105/211 (50%)
		RRM1_U1A_like	9..86	CDD:240692	47/76 (62%)
		RRM2_U1A_like	130..201	CDD:240693	36/70 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159498
Domainoid	1	1.000	66	1.000	Domainoid score	I6582
eggNOG	1	0.900	-	-		E1_KOG4206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3380
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54412
OrthoDB	1	1.010	-	-		D1608132at2759
OrthoFinder	1	1.000	-	-		FOG0001375
OrthoInspector	1	1.000	-	-		otm14394
orthoMCL	1	0.900	-	-		OOG6_100753
Panther	1	1.100	-	-	O	PTHR10501
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1270
SonicParanoid	1	1.000	-	-		X1105
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.750