Protein Alignment Cdk7 and cdk5

DIOPT Version :10

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001072776.1
• Gene: cdk5 / 780236
• XenbaseID: XB-GENE-1010261
• Length: 292
• Species: Xenopus tropicalis
• Alignment Length: 293
• Identity: 131/293 - (44%)
• Similarity: 186/293 - (63%)
• Gaps: 11/293 - (3%)

  Fly    10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENI 74
            ::|.||..:|||.:.||:||::..|::|||:|:::   .:|..:|:..:|||||.:|:||:|:||
 Frog     2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVR---LDDDDEGVPSSALREICLLKELKHKNI 63

  Fly    75 IGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLK 139
            :.|.||......::|||::.|.||:.........|....:|::....||||.:.|...:||||||
 Frog    64 VRLHDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLGFCHSRNVLHRDLK 128

  Fly   140 PNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILA 204
            |.|||:|.:|.||:.|||||::||.|.|.|:..|||.|||.|::||||:.|.|.:|||:.|||.|
 Frog   129 PQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFA 193

  Fly   205 ELM-LRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGT-PLDNI---FTAA 264
            ||. ...|..||:...|||.|||..||||||.:||.::||.||..:..:|.| .|.|:   ..|.
 Frog   194 ELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATMSLVNVVPKLNAT 258

  Fly   265 GNDLIHLMQRLFAMNPLRRVSCREALSMPYFAN 297
            |.|   |:|.|...||::|:...|||..||||:
 Frog   259 GRD---LLQNLLKCNPVQRICADEALQHPYFAD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	STKc_CDK7	11..308	CDD:270833	131/292 (45%)
cdk5	NP_001072776.1	STKc_CDK5	3..286	CDD:143344	128/288 (44%)