Protein Alignment Cdk7 and Cdk8

DIOPT Version :9

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 116/337 - (34%)
• Similarity: 179/337 - (53%)
• Gaps: 53/337 - (15%)

  Fly    18 LGEGQFATVYKA--RDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENIIGLVDV 80
            :|.|.:..||||  ::|...:..|:|:| .|:      |::.:|.|||.:|:||:|:|:|.|:.|
  Fly    27 VGRGTYGHVYKAKWKETSDGKEYALKQI-DGT------GLSMSACREIALLRELKHQNVITLIRV 84

  Fly    81 FGQLSN----VSLVFDFMDTDLEVIIK--------DNKIILTQANIKAYAIMTLKGLEYLHLNWI 133
            |  ||:    |.|:.|:.:.||..|||        ..::::.:..:|:.....|.|:.|||.||:
  Fly    85 F--LSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLLYQILDGIHYLHSNWV 147

  Fly   134 LHRDLKPNNLLV----NSDGILKIGDFGLAKSFGSPNRIYTH---HVVTRWYRSPELLFGARQYG 191
            |||||||.|:||    |..|.:||.|.|.|:.|.:|.:....   .|||.|||:||||.|||.|.
  Fly   148 LHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYT 212

  Fly   192 TGVDMWAVGCILAELMLRVP-FMPGDSDL--------DQLTRIFSTLGTPTEAEWPHLSKLHDYL 247
            ..:|:||:|||.|||:...| |.....|:        |||.|||:.:|.|.:.:|..:.|:.::.
  Fly   213 KAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHH 277

  Fly   248 QF-RNFPGTPLDNIFTA---------AGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPT 302
            .. ::|..:.......|         ..:...||:|:|..|:|.:|::..:|:...||..:|.||
  Fly   278 TLTKDFKRSTYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDQYFQEEPQPT 342

  Fly   303 ----VGPKLPMP 310
                .|..:|.|
  Fly   343 QDVFAGCPIPYP 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	PTZ00024	6..308	CDD:240233	114/333 (34%)
		STKc_CDK7	11..308	CDD:270833	114/333 (34%)
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	108/316 (34%)
		S_TKc	22..335	CDD:214567	108/316 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442383
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940