Protein Alignment Cdk7 and Cdk4

DIOPT Version :9

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 309
• Identity: 115/309 - (37%)
• Similarity: 174/309 - (56%)
• Gaps: 39/309 - (12%)

  Fly    12 YAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQEL---QHEN 73
            |.:|:.:|||.:.|||:|||.:|..|||:||::....|   :|:..:.||||.:|::|   .|.|
  Fly    26 YQELNIIGEGAYGTVYRARDVITGNIVALKKVRISLNE---NGVPMSTLREISLLKQLNASNHAN 87

  Fly    74 IIGLVDVF------GQLSNVSLVFDFMDTDL-EVIIKDNKIILTQANIKAYAIMTLKGLEYLHLN 131
            |:.|.:|.      |||. :.|||:.::.|| ::|.:..|..::...|:..:...|.|:::||.:
  Fly    88 IVKLYEVCQFLERDGQLL-ILLVFEHVEQDLSDLIDRLPKSGMSPPTIQRLSRELLTGVDFLHSH 151

  Fly   132 WILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDM 196
            .|:||||||.||||:|.|.|||.||||||::||..:: |..|||.|||:||:|. |:.|.:.||:
  Fly   152 RIIHRDLKPQNLLVSSQGHLKIADFGLAKTYGSEMKL-TSVVVTLWYRAPEVLL-AQPYNSTVDI 214

  Fly   197 WAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWP--------HLSKLHDYLQFRNFP 253
            |:..||:.|:..|....||.|:.:||.|||...|.|||.:||        |..:.|        |
  Fly   215 WSAACIIFEMFNRRALFPGTSEKNQLDRIFELTGRPTEQQWPQTISVALEHFPQRH--------P 271

  Fly   254 GTPLD---NIFTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKP 299
            ..|.|   ::...|.:    |:.::.:.:...|.|....|...||..:|
  Fly   272 KRPKDFCPHLCKYADD----LLNKMLSYDLHLRPSALACLEHDYFQQEP 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	PTZ00024	6..308	CDD:240233	115/309 (37%)
		STKc_CDK7	11..308	CDD:270833	115/309 (37%)
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	112/303 (37%)
		S_TKc	26..312	CDD:214567	112/303 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940