Protein Alignment Cdk7 and CDKL4

DIOPT Version :9

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001333840.1
• Gene: CDKL4 / 344387
• HGNCID: 19287
• Length: 379
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 120/352 - (34%)
• Similarity: 184/352 - (52%)
• Gaps: 33/352 - (9%)

  Fly    10 ERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQELQHENI 74
            |:|.||:..|||.:..|:|.|:..:.|:|||||..:...:..   :.:.|||||::|::|:|.|:
Human     2 EKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPV---VKKIALREIRMLKQLKHPNL 63

  Fly    75 IGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWILHRDLK 139
            :.|::||.:...:.|||::.|..|...::.|...:....||:....||:.|.:.|::..:|||:|
Human    64 VNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNCIHRDIK 128

  Fly   140 PNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAVGCILA 204
            |.|:|:...||:||.|||.|:.. .|...||.:|.|||||:||||.|..|||:.||:||:||:.|
Human   129 PENILITKQGIIKICDFGFAQIL-IPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFA 192

  Fly   205 ELMLRVPFMPGDSDLDQLTRIFSTLG--TPTEAEWPHLSKLHDYLQFRNFPG----TPLDNIFTA 263
            ||:...|..||.||:|||..|..|||  .|....   :.|.:.:....:.|.    ..|:..|:.
Human   193 ELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQS---IFKSNGFFHGISIPEPEDMETLEEKFSD 254

  Fly   264 AGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLPMPSAILAAKEGAN------- 321
            .....::.|:....|||..|::|.:.|...||.:.....:..|        |..||.|
Human   255 VHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIKRK--------ARNEGRNRRRQQQA 311

  Fly   322 PQTGDTKPALKRKLV-----ETTVRGN 343
            |::...:..||.|:.     ||...||
Human   312 PKSAFPRLFLKTKICQVQRNETQTSGN 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	PTZ00024	6..308	CDD:240233	108/303 (36%)
		STKc_CDK7	11..308	CDD:270833	107/302 (35%)
CDKL4	NP_001333840.1	[NKR]KIAxRE	45..51		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910