Protein Alignment Cdk7 and mcs6

DIOPT Version :9

• Sequence 1: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_596349.1
• Gene: mcs6 / 2540471
• PomBaseID: SPBC19F8.07
• Length: 335
• Species: Schizosaccharomyces pombe
• Alignment Length: 351
• Identity: 153/351 - (43%)
• Similarity: 228/351 - (64%)
• Gaps: 24/351 - (6%)

  Fly     7 DKTER--YAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKILQEL 69
            :|:::  |.|...:|||.:|.|:..|...||:.||:||||.|   ..:|||:.:||||||.|:|.
pombe     4 EKSDKWTYVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVG---QFKDGIDISALREIKFLRES 65

  Fly    70 QHENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHLNWIL 134
            :|:|:|.|||||...||::::.:|:|:|||::|||..|:...|:||::.:|.|:||.::|..:||
pombe    66 RHDNVIELVDVFSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFIL 130

  Fly   135 HRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVDMWAV 199
            ||||||||||::|||:||:.||||::.||:|:.: :|.|:|||||.|||..|.|.||||||||:|
pombe   131 HRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHM-SHQVITRWYRPPELFMGCRSYGTGVDMWSV 194

  Fly   200 GCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNF--PGTPLDNIFT 262
            |||.||||||.|::||:||||||..||..||||.......:.:|.:|::.::.  |...::.:|:
pombe   195 GCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKHIPPPNGGMEALFS 259

  Fly   263 AAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLPMPSAILAAKEGANPQTGDT 327
            |||::.|.|::.:...||.||.:.::||...||:..|.||....||..    ..:||....:.|.
pombe   260 AAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPSLLPRK----GGEEGIKHVSSDL 320

  Fly   328 KPALKRKLVETTVRGNGLAQKKRLQF 353
            :            |.|....:..::|
pombe   321 Q------------RQNNFPMRANIKF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk7	NP_511044.1	PTZ00024	6..308	CDD:240233	145/304 (48%)
		STKc_CDK7	11..308	CDD:270833	144/300 (48%)
mcs6	NP_596349.1	STKc_CDK7	11..305	CDD:270833	144/297 (48%)
		Pkinase	11..292	CDD:278497	139/284 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	289	1.000	Domainoid score	I285
eggNOG	1	0.900	-	-		E1_KOG0659
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1363
Inparanoid	1	1.050	296	1.000	Inparanoid score	I617
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003675
OrthoInspector	1	1.000	-	-		oto100591
orthoMCL	1	0.900	-	-		OOG6_103547
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R249
SonicParanoid	1	1.000	-	-		X2548
TreeFam	1	0.960	-	-
	13	12.850