DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rpn13R and Adrm1

DIOPT Version :9

Sequence 1:	NP_572205.1	Gene:	Rpn13R / 31433	FlyBaseID:	FBgn0029745	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_062796.2	Gene:	Adrm1 / 56436	MGIID:	1929289	Length:	407	Species:	Mus musculus

Alignment Length:	389	Identity:	116/389 - (29%)
Similarity:	175/389 - (44%)	Gaps:	87/389 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SNAHNLVEYKAGRMVLLGKMVEPDDRKGLLFVRRSADDNQLHIHWMDRRSGSVELDIVATPGVLE 68
            |:...|||::||:|.|.|..|.||.||||:::::: ||:.:|..|.||.||:||.|::..|...|
Mouse    18 SSTKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQT-DDSLIHFCWKDRTSGTVEDDLIIFPDDCE 81

  Fly    69 FRRIDQCKTGRVYVLKYTRSTQRYFFWMQELQADGDALFCQRVNELI----------ASGERQRD 123
            |:|:.||.:|||||||:...::|.||||||.:.|.|...|::|||.:          |||. ...
Mouse    82 FKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNECLNNPPMPGSLGASGS-SGH 145

  Fly   124 EIAA--AEGDMDT---DADHTTARR-----------GFGGSENPQILEEMLVETQATWLPANRSL 172
            |::|  .||.:.:   :..|:...:           |.|....|.:...:    .::..||:.|.
Mouse   146 ELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLL----GSSGPPASSSS 206

  Fly   173 NHWQTGDAMEEP----------PLPFA---------DPDANTDTDTDTYTSES------------ 206
            :..::..|...|          |.|.|         .|..::...|.|..|.:
Mouse   207 SSSRSQSAAVTPSSSTSSARATPAPSAPAAASATSPSPAPSSGNGTSTAASPTQPIQLSDLQSIL 271

  Fly   207 ----------GIQTFDLAAVLRLHGAEAVDKVLSCPSRREKLMAQLPKDHEAMDEQSDILEHLHS 261
                      |.|..|||:||.   .|.:..:|:....:|:|:..||..........:|...|.|
Mouse   272 ATMNVPAGPGGSQQVDLASVLT---PEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTS 333

  Fly   262 AQFYESLSSFSVGLHSGALRKSLEPLL-QSDDNREALNAAQVGDVERFLRELERN------DGD 318
            .||.::|..||..|.||    .|.||: |.....||:.||..||||.|.:.::.|      :||
Mouse   334 PQFQQALGMFSAALASG----QLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKSDPKEGD 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13R	NP_572205.1	PH_Rpn13	10..115	CDD:270124	51/104 (49%)
Rpn13R	NP_572205.1	RPN13_C	204..312	CDD:293158	38/130 (29%)
Adrm1	NP_062796.2	PH_Rpn13	24..128	CDD:270124	51/104 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..259		12/62 (19%)
		RPN13_C	274..381	CDD:293158	37/113 (33%)
		Interaction with UCHL5. /evidence=ECO:0000250	362..407		12/32 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..407		3/13 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838145
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003818
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102724
Panther	1	1.100	-	-	O	PTHR12225
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2662
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.700