DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rpn13R and adrm1

DIOPT Version :9

Sequence 1:	NP_572205.1	Gene:	Rpn13R / 31433	FlyBaseID:	FBgn0029745	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_989049.1	Gene:	adrm1 / 394646	XenbaseID:	XB-GENE-489445	Length:	404	Species:	Xenopus tropicalis

Alignment Length:	375	Identity:	113/375 - (30%)
Similarity:	167/375 - (44%)	Gaps:	75/375 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SNAHNLVEYKAGRMVLLGKMVEPDDRKGLLFVRRSADDNQLHIHWMDRRSGSVELDIVATPGVLE 68
            |::..|||::||:|.|.|..|.||.||||:::::: ||:.:|..|.||.|||||.|::..|...|
Frog    17 SSSKYLVEFRAGKMSLKGSTVTPDKRKGLVYIQQT-DDSLIHFCWKDRTSGSVEDDLIIFPDDCE 80

  Fly    69 FRRIDQCKTGRVYVLKYTRSTQRYFFWMQELQADGDALFCQRVNELI------------ASGERQ 121
            |:|:.||.||||||||:...::|.||||||.:.|.|..:|::|||.:            .||..:
Frog    81 FKRVSQCTTGRVYVLKFKAGSKRLFFWMQEPKTDKDEEYCRKVNEYLNNPPMPGALGGSGSGGHE 145

  Fly   122 RDEIAAAEGDMDT---DADHT--------TARRGFGG---------------------------- 147
            ...: ..||.:.:   :..|.        |...|.||
Frog   146 LSAL-GGEGGLQSLLGNMSHNQLMQLIGPTGLGGLGGLGALTGPGLASLLGSGGPTTSSSSSSSR 209

  Fly   148 SENPQILEEMLV-ETQATWLPANR------------SLNHWQTGDAMEEPPLPFADPDANTDTDT 199
            |::..:...... .|:.|..||..            |.|...:.......|:..:|......|..
Frog   210 SQSAAVTPSSTTSSTRTTSAPAAPAAAPATTPSPAVSSNDGASAATSPTQPIQLSDLQNILATMN 274

  Fly   200 DTYTSESGIQTFDLAAVLRLHGAEAVDKVLSCPSRREKLMAQLPKDHEAMDEQSDILEHLHSAQF 264
            ...|.|.| |..|||:||.   .|.:..:|:....:|:||..||..........:|...|.|.||
Frog   275 VPATGEGG-QQVDLASVLT---PEIMAPILANAEVQERLMPYLPSGESLPQTADEIQNTLTSPQF 335

  Fly   265 YESLSSFSVGLHSGALRKSLEPLL-QSDDNREALNAAQVGDVERFLRELE 313
            .::||.||..|.||    .|.||: |.....:|::||..||:|.|.:.::
Frog   336 QQALSMFSAALASG----QLGPLMSQFGLPADAVDAANKGDIEAFAKAMQ 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rpn13R	NP_572205.1	PH_Rpn13	10..115	CDD:270124	53/104 (51%)
Rpn13R	NP_572205.1	RPN13_C	204..312	CDD:293158	38/108 (35%)
adrm1	NP_989049.1	PH_Rpn13	23..127	CDD:270124	53/104 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	195..258		7/62 (11%)
		RPN13_C	273..380	CDD:374621	39/114 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	377..404		0/5 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1479349at2759
OrthoFinder	1	1.000	-	-		FOG0003818
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12225
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020