DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32767 and Gm14434

DIOPT Version :9

Sequence 1:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster
Sequence 2:	NP_001095274.1	Gene:	Gm14434 / 668039	MGIID:	3702417	Length:	498	Species:	Mus musculus

Alignment Length:	268	Identity:	81/268 - (30%)
Similarity:	116/268 - (43%)	Gaps:	11/268 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   442 QQQQQQQAQQEQQRQQQQQLQQQQQQQQTHPVKHSASGSSSTNNNSTTNSTNSNNNTPAATATVT 506
            :.::...|:|..:..|..:....:..:|.|.:||:.......|.......|.:.......|.|..
Mouse    64 RHERSCSAEQPSEFIQCGKAFAYESGRQRHQIKHNGEKHHDCNQCGKDFRTWNVLQIHKRTHTGE 128

  Fly   507 TSYQCVECVEKFDSKELFDIHRSGHA--NNMKCAICNMVLKSLKNYEKHCLRC----KPYECQIC 565
            ..|.|.:|.:.|.......||...||  ...:|..|....|...|.:.| .|.    |||||..|
Mouse   129 KPYDCKQCGKVFARSCHLQIHNRTHAGEKQYECNQCGKAFKRRINLQIH-KRTHTGEKPYECNQC 192

  Fly   566 GRVVRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFS 630
            |:.........||.|.|||::    .|:|:.|.|.|....:.::||:.|.......|..|||.|:
Mouse   193 GKAFASSGELQKHKRTHTGEK----PYECKQCGKAFSQSSHLRIHKRTHTGEKPYECNQCGKAFA 253

  Fly   631 ALASLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKICKKKLHTQSSLQTHM 695
            ....|:.|.:.|:|.|.::|..|||.|....:|..|.||||||.|:|||.|.|......:||.|.
Mouse   254 RSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHKHERTHTGDKPYECKQCGKAFAVIYTLQMHK 318

  Fly   696 QVHLRDQP 703
            :.|..|:|
Mouse   319 RTHTGDKP 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	5/19 (26%)
		C2H2 Zn finger	562..582	CDD:275368	6/19 (32%)
		C2H2 Zn finger	594..614	CDD:275368	6/19 (32%)
		C2H2 Zn finger	622..642	CDD:275368	7/19 (37%)
		zf-C2H2	648..670	CDD:278523	8/21 (38%)
		C2H2 Zn finger	650..670	CDD:275368	8/19 (42%)
		zf-H2C2_2	662..684	CDD:290200	13/21 (62%)
		C2H2 Zn finger	678..698	CDD:275368	7/19 (37%)
Gm14434	NP_001095274.1	KRAB	3..44	CDD:396083
		COG5048	74..486	CDD:227381	79/258 (31%)
		C2H2 Zn finger	79..97	CDD:275368	3/17 (18%)
		C2H2 Zn finger	105..125	CDD:275368	2/19 (11%)
		C2H2 Zn finger	133..153	CDD:275368	5/19 (26%)
		C2H2 Zn finger	161..181	CDD:275368	6/20 (30%)
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		C2H2 Zn finger	329..349	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
		C2H2 Zn finger	385..405	CDD:275368
		C2H2 Zn finger	413..433	CDD:275368
		C2H2 Zn finger	441..461	CDD:275368
		C2H2 Zn finger	469..488	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100