DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32767 and Zfp112

DIOPT Version :9

Sequence 1:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster
Sequence 2:	XP_036009176.1	Gene:	Zfp112 / 57745	MGIID:	1929115	Length:	883	Species:	Mus musculus

Alignment Length:	198	Identity:	75/198 - (37%)
Similarity:	100/198 - (50%)	Gaps:	9/198 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   509 YQCVECVEKFDSKELFDIHRSGHANNMK--CAICNMVLKSLKNYEKHC---LRCKPYECQICGRV 568
            |||.||.:.|..|.....|:|.|:....  |.:|..........:.|.   .|.|||:|::||:.
Mouse   667 YQCHECGKNFSQKSYLQSHQSVHSGERPHICEVCGKGFSQRAYLQGHLRVHTRVKPYKCEVCGKG 731

  Fly   569 VRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALA 633
            .........|.|||||    |..:|||.|.|.|......:.|::||.|.....|:.|||.||..:
Mouse   732 FSQGSRLEAHQRVHTG----RKPFKCETCTKGFSESSRLQAHQRIHEEGRPYKCDQCGKGFSGYS 792

  Fly   634 SLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKICKKKLHTQSSLQTHMQVH 698
            ||:.|.::|:|.|.:||:||||||.||.||:.|.|.|||:.|:.|..|.|.....|.|..|.:.|
Mouse   793 SLQAHHRVHTGEKPYKCEVCGKGFSQRSNLQAHQRVHTGEKPYTCDACGKGFRWSSGLLIHQRAH 857

  Fly   699 LRD 701
            ..|
Mouse   858 SSD 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	3/22 (14%)
		C2H2 Zn finger	562..582	CDD:275368	5/19 (26%)
		C2H2 Zn finger	594..614	CDD:275368	6/19 (32%)
		C2H2 Zn finger	622..642	CDD:275368	9/19 (47%)
		zf-C2H2	648..670	CDD:278523	14/21 (67%)
		C2H2 Zn finger	650..670	CDD:275368	13/19 (68%)
		zf-H2C2_2	662..684	CDD:290200	10/21 (48%)
		C2H2 Zn finger	678..698	CDD:275368	6/19 (32%)
Zfp112	XP_036009176.1	KRAB	12..72	CDD:214630
		COG5048	251..716	CDD:227381	13/48 (27%)
		C2H2 Zn finger	481..498	CDD:275368
		C2H2 Zn finger	529..549	CDD:275368
		C2H2 Zn finger	557..577	CDD:275368
		C2H2 Zn finger	585..605	CDD:275368
		C2H2 Zn finger	613..633	CDD:275368
		C2H2 Zn finger	641..661	CDD:275368
		C2H2 Zn finger	669..689	CDD:275368	7/19 (37%)
		COG5048	<674..842	CDD:227381	64/171 (37%)
		C2H2 Zn finger	697..717	CDD:275368	3/19 (16%)
		C2H2 Zn finger	725..745	CDD:275368	5/19 (26%)
		C2H2 Zn finger	753..773	CDD:275368	6/19 (32%)
		C2H2 Zn finger	781..801	CDD:275368	9/19 (47%)
		C2H2 Zn finger	809..829	CDD:275368	13/19 (68%)
		C2H2 Zn finger	837..857	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BNZS
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900