DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32767 and Zfp956

DIOPT Version :9

Sequence 1:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster
Sequence 2:	XP_006236479.1	Gene:	Zfp956 / 312301	RGDID:	1304879	Length:	573	Species:	Rattus norvegicus

Alignment Length:	705	Identity:	136/705 - (19%)
Similarity:	219/705 - (31%)	Gaps:	244/705 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 IQQQQQQQQHHLLNGRRIIIQATGNSSVLAASDIKEEDEEEEDPELNDENLQDIEEEAQAAEADE 236
            :|||.|             ||.|..|.:...:.|:..:::.|...::.:||:.....|:....|.
  Rat    16 LQQQAQ-------------IQCTETSLLALLAAIQAVEKKTESQGIHLQNLEVRTGSAEKKLTDF 67

  Fly   237 EPETTAHLSTQV-------------------KLELEED-----------------DE-------- 257
            | :|...||:|:                   :||..|:                 ||
  Rat    68 E-KTAVELSSQLEGKWAVLGTLLQEYGLLQRRLENLENQMQNRNPWVLRLPPSSKDEAPKVSVIT 131

  Fly   258 ------MPDEEEEEDEDDDEEL-QHGQLEYQISAATQTAGAATSSAAGGAATAGGGSQQLVQLPA 315
                  .|:::|...||..:|| :|
  Rat   132 EEVTGCFPEQQEGSPEDWQKELCKH---------------------------------------- 156

  Fly   316 GSIVSTTTHRLSVPVTEAALVQLQRRPVYISNAVGGLTAGATYVRMPAAAVISRSPMTVLNVVQQ 380
                                |..:||.|     :|.|..|..           .|..:||..::|
  Rat   157 --------------------VAKERREV-----LGSLETGQL-----------ESAPSVLPWIKQ 185

  Fly   381 ALPATQLILQTQQQQTPAAAAAEQQLA----------LALEQQRQQQEQQAQQQRQQQQQ----- 430
               ..::..::.|:.|.|:..:|..||          ||.|.....:....::...:|..
  Rat   186 ---EEEVCEKSLQETTSASLCSETWLANKKRTLEGMSLAPEPSWVTEGGPGKEDFSEQGTCGDLL 247

  Fly   431 ---QEQQRQQQQQQQQQQQQQAQQEQQRQQQQQLQQQQQQQQTHPVKHSASGSSSTNNNSTTNST 492
               :|::.....:..|.|...|.:..:..|...:|:..:|     :::|..||....:.....|.
  Rat   248 PVCREREASSLPRGSQSQSVSAAEGTENGQNFNVQELSKQ-----LEYSHHGSQPFASLQCPQSA 307

  Fly   493 ------NSNNNTPAATATVTTSYQCVECVEKFDSKELFDIHRSGHANNMKCAICNMVLKSLKNYE 551
                  ..|...|||    ..:|.||:|.:.|..:.....|...|...
  Rat   308 AQQVTLTRNRRAPAA----QRAYTCVQCGKSFVHQSTLTTHYRTHTGE----------------- 351

  Fly   552 KHCLRCKPYECQICGRVVRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNE 616
                  |||:|..|.:........::|.|.|||::    .:.|..|.:.|........|::.|..
  Rat   352 ------KPYKCAECEKRFGRLSTLLEHQRTHTGER----PFPCAQCGRRFGRLSTLVEHRRTHTG 406

  Fly   617 NVNLTCEICGKVFSALASLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKIC 681
            .....|..|.|.|:.||:|..|..:|||....:|..||..|..:.:...|.|:|:.:..|.|..|
  Rat   407 EKPFPCTQCDKRFTRLANLTVHQSVHSGEHAFQCTQCGSCFTHKPSFLRHLRSHSQEKRFTCGQC 471

  Fly   682 KKKLHTQSSLQTHMQVHLRDQPGAAAAAATAAGAASSKASNS--------SNSSNSSNSSSSNSS 738
            .|....:|.|..|...|        |.:|::|..|..::|.|        ..|:....||..:.|
  Rat   472 GKSFTCRSWLVRHQSSH--------AHSASSAYVACERSSPSYVPPTGLFKGSARGKFSSDPSVS 528

  Fly   739 SNGVSAAVSAATTTTTIVKLEPPHEIERPGTSSNQQLQQSQHHQMELDDQSGLSG 793
            .......||.                :.......|||  |.|      ||..|.|
  Rat   529 PRSKDTRVSQ----------------DHKAYGGGQQL--SDH------DQESLVG 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	0/19 (0%)
		C2H2 Zn finger	562..582	CDD:275368	4/19 (21%)
		C2H2 Zn finger	594..614	CDD:275368	4/19 (21%)
		C2H2 Zn finger	622..642	CDD:275368	8/19 (42%)
		zf-C2H2	648..670	CDD:278523	6/21 (29%)
		C2H2 Zn finger	650..670	CDD:275368	6/19 (32%)
		zf-H2C2_2	662..684	CDD:290200	6/21 (29%)
		C2H2 Zn finger	678..698	CDD:275368	6/19 (32%)
Zfp956	XP_006236479.1	C2H2 Zn finger	302..320	CDD:275368	2/17 (12%)
		zf-C2H2	326..348	CDD:395048	6/21 (29%)
		C2H2 Zn finger	328..348	CDD:275368	5/19 (26%)
		zf-H2C2_2	341..365	CDD:404364	7/46 (15%)
		C2H2 Zn finger	356..376	CDD:275368	4/19 (21%)
		COG5048	380..>445	CDD:227381	18/68 (26%)
		C2H2 Zn finger	384..404	CDD:275368	4/19 (21%)
		zf-H2C2_2	397..421	CDD:404364	6/23 (26%)
		C2H2 Zn finger	412..432	CDD:275368	8/19 (42%)
		C2H2 Zn finger	440..460	CDD:275368	6/19 (32%)
		zf-H2C2_2	455..477	CDD:404364	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24393
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100