DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32767 and prz1

DIOPT Version :9

Sequence 1:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster
Sequence 2:	NP_593073.1	Gene:	prz1 / 2541806	PomBaseID:	SPAC4G8.13c	Length:	681	Species:	Schizosaccharomyces pombe

Alignment Length:	816	Identity:	138/816 - (16%)
Similarity:	235/816 - (28%)	Gaps:	274/816 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 INDSALSQQIEFILQDAPMEQD-----------DDPHQHTHVHHHHHSQHHPHSHSHQQQQQQHL 93
            :||::|:        |.|:.:|           .:|.:: ::.|.|.:...|...|
pombe    40 MNDTSLA--------DIPLFEDTLASEVSSSLISNPSKN-NIQHLHPNTSEPFKTS--------- 86

  Fly    94 QQQQQQQQHHHPHHHLKLDNSSNNHP--------PTAAAAAAAVAVAATTAATAAAATNNSASFS 150
              .:..:...:|.        :.|.|        .|:.:...:.||...:.:..:..:|:..:|.
pombe    87 --SKSDEYDSYPR--------TGNVPTFSFTELNDTSVSGFGSQAVFENSVSPLSNPSNSPQAFD 141

  Fly   151 SNSSSSNSNNSN------------------------HLDNQQQLLIQQQQQQQQHHLLNGRRIII 191
            ....||:::|:|                        ::|:.|.|.:.:.....:....:..:::.
pombe   142 LTQGSSSTHNANDFTVNNVGSRRQSIYEFNIGIPSSNIDSSQFLPVSRAIAASEISPSSSPQLLT 206

  Fly   192 Q-----ATGNSS---------------------VLAASDIKEEDEEE------EDPELNDENLQD 224
            .     :..|.|                     |::.:...|.|.|.      |||.|..||.|:
pombe   207 SFLPSGSVSNPSSPYLQGSVGALYEADAFNFVDVMSQASGTEVDSERFPSVDFEDPSLLMENQQN 271

  Fly   225 IEEEAQAAEADEEPET---------------------TAHLSTQVKLELEEDDEMPDEEEEEDED 268
            |......|:..:.|.:                     |.:.:....::|..:...|....|  ..
pombe   272 ITGTGSFADYLQPPSSGSLGAFTNASPGESNTGIDFDTDNTNLNPSVDLLSNHSTPSFIFE--NS 334

  Fly   269 DDEELQHGQLEYQISAATQTAGAATSSAAGGAATAGGGSQQLVQLPAGSIVSTTTHRLSVPVTEA 333
            ...|..|....|.:    ..:|...:|.....:|....:....:..|.:  |.|||... |::
pombe   335 PSAEFSHQSSPYLV----PNSGRTLNSENARESTIRSVNSPFSEDHADA--SLTTHVFD-PIS-- 390

  Fly   334 ALVQLQRRPVYISNAVGGLTAGATYVRMPAAAVISRSPMTVLNVVQQALPATQLILQTQQQQTPA 398
                    |..:||:|....:. .:...|...|:..||..  :....:|||..| |||....|
pombe   391 --------PTALSNSVLNYDSN-NFSGTPQINVVPSSPSK--SQSGPSLPANPL-LQTDISIT-- 441

  Fly   399 AAAAEQQLALALEQQRQQQEQQAQQQRQQQQQQEQQRQQQQQQQQQQQQQAQQEQQRQQQQQLQQ 463

pombe   442 ----------------------------------------------------------------- 441

  Fly   464 QQQQQQTHPVKHSASGSSSTNNNSTTNSTNSNNNTPAATATVTTSYQCVECVEKFDSKELFDIHR 528
              ..|...||    ||..:.|.|| .:..|:|...|..:.|.|..::......:||:.|......
pombe   442 --YSQSASPV----SGQPAMNENS-YDLQNANLCAPEMSPTYTARHRSNSAGSRFDAYEPIPQLY 499

  Fly   529 SGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRVVRFRPNFIKHMRVHTGQQSERHKYK 593
            :..:::.:|...|...:.|...|....:...|   :..|..|.|...:..:..:..:.|...|.|
pombe   500 THFSHSSECLSVNQDTELLGKIENDNSKSNDY---LSVRNTRPRSRSLNSLVGNKSENSSSSKAK 561

  Fly   594 CEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALASLRGHSKLHSGVKLHKCDVCGKGFG 658
            .|                  .....|..|...|                          |.|.|.
pombe   562 SE------------------SKSQGNYVCTFAG--------------------------CNKRFT 582

  Fly   659 QRYNLKIHARTHTGDFPFECKICKKKLHTQSSLQTHMQVHLRDQPGAAAAAATAAGA--ASSKAS 721
            :.||||.|..|||...||:|.||||....|...:.|.|:|    .|..|.|......  |...|.
pombe   583 RAYNLKSHMNTHTNYRPFQCSICKKSFARQHDKRRHEQLH----TGIKAFACVTCNQRFARMDAL 643

  Fly   722 NSSNSSNSSNSSSSNSSSNGVSAAVSAATTTTTIVK 757
            |....|....:....::..|:....|..|...:..|
pombe   644 NRHYKSEVGQNCLRTATERGIQVPPSRKTAVASTSK 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	4/19 (21%)
		C2H2 Zn finger	562..582	CDD:275368	3/19 (16%)
		C2H2 Zn finger	594..614	CDD:275368	1/19 (5%)
		C2H2 Zn finger	622..642	CDD:275368	2/19 (11%)
		zf-C2H2	648..670	CDD:278523	8/21 (38%)
		C2H2 Zn finger	650..670	CDD:275368	8/19 (42%)
		zf-H2C2_2	662..684	CDD:290200	13/21 (62%)
		C2H2 Zn finger	678..698	CDD:275368	8/19 (42%)
prz1	NP_593073.1	COG5048	121..620	CDD:227381	110/642 (17%)
		zf-C2H2	570..594	CDD:278523	10/49 (20%)
		C2H2 Zn finger	577..594	CDD:275368	8/16 (50%)
		zf-H2C2_2	586..611	CDD:290200	14/24 (58%)
		C2H2 Zn finger	602..622	CDD:275368	8/19 (42%)
		zf-H2C2_2	616..639	CDD:290200	6/26 (23%)
		C2H2 Zn finger	630..648	CDD:275368	3/17 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100