DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32767 and Zfp148

DIOPT Version :9

Sequence 1:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster
Sequence 2:	XP_006522161.1	Gene:	Zfp148 / 22661	MGIID:	1332234	Length:	800	Species:	Mus musculus

Alignment Length:	833	Identity:	153/833 - (18%)
Similarity:	284/833 - (34%)	Gaps:	275/833 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   379 QQALPATQLILQTQQQQTPAAAAAEQQLALALEQQRQQQEQQAQQQRQQQQQQEQQR-----QQQ 438
            |:.|.|.:::.:::.:|..  ..:..:|.:..|..:..:||....:|..|..|....     :|:
Mouse    55 QEILAADEVLQESEMRQQD--MISHDELMVHEETVKNDEEQMDTHERLPQGLQYALNVPISVKQE 117

  Fly   439 QQQQQQQQQQAQQEQQRQQQQQLQQQQQQQQTHPVKHSASGSSSTNNNSTTNSTNSNNNTPAATA 503
            .......:|..:.::|.::...||::::::|..|.|..
Mouse   118 ITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKVR--------------------------- 155

  Fly   504 TVTTSYQCVECVEKFDSKELFDIHRSGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRV 568
                           |..::..|:..|          ::.||:.|:          :.|:.|...
Mouse   156 ---------------DCAKILTINEDG----------SLGLKTPKS----------HVCEHCNAA 185

  Fly   569 VRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALA 633
            .|...:..:|:.:|||::    .::|..|...|:. :|.
Mouse   186 FRTNYHLQRHVFIHTGEK----PFQCSQCDMRFIQ-KYL-------------------------- 219

  Fly   634 SLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKICKKKLHTQSSLQTHMQVH 698
             |:.|.|:|:|.|..:||.||..|.|:|:::.|.|||:|:.|::|:.|.:.......:..|.::.
Mouse   220 -LQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMC 283

  Fly   699 LRDQPGAAAAAATAAGAASSKASNSSNSSNSSNS--------SSSNSSSNGVSAAVSAAT----- 750
            ..:........|...|..:|:..:..::|...||        :...||.....:.:..:.
Mouse   284 HENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKTEKKSSGMDKESVLDKSDLKKDK 348

  Fly   751 -------TTTTIVK---------LEPPH-------------EIERP---------GTSSNQQLQQ 777
                   :::|.||         :|.||             ||..|         ..|..|.|:|
Mouse   349 NDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQ 413

  Fly   778 SQ--------------HHQMELDDQSGLSGDE-----------EDGSGGGMNSSSH--------- 808
            ||              .:..||.|:..|...|           ::|....::||::
Mouse   414 SQTISPLSSYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLK 478

  Fly   809 ---IVNATTNR-----LTTGEDSSESS---NASLHLNQHSSTSS---SPASQHQV-SSHQQHV-- 856
               .:.|.:|.     |..|..:|:.|   .|...:...|:|:|   |.|...:: |:|.::|
Mouse   479 KKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDESTTASILDSQALNVEIKSNHDKNVIP 543

  Fly   857 ---------HQQQQQQQQSQQQYLV--SAPTRTIVIKNY-MQQGSQQQQQQQQQQQHTSDPTPVL 909
                     |...:...|.:..:.|  :..|.:|.|.:. :.:.:|.:......|..:||...:|
Mouse   544 DEVLQTLLDHYSHKPNGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANML 608

  Fly   910 --HAQVIQSGAGTSNGSGNTSSTNSSSNS-STNIVTTNAGGNLSN-------GSQLIRKTPIIHH 964
              :::.:|...      ..||..::..|| |.|.||.|.  .|.|       ..|:....||
Mouse   609 QEYSKFLQQAL------DRTSQNDAYLNSPSLNFVTDNQ--TLPNPPAFSSIDKQVYAAMPI--- 662

  Fly   965 STGSSNGSGGSALTSVVQQTG-------VISPAQSP---SSSSTSCSSSTVLVSKATGVPLSIAS 1019
                  .|..|.:.|.::.|.       ::..:|.|   |...|:.:|:|
Mouse   663 ------NSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASAT--------------- 706

  Fly  1020 SAAAALGGSTIIRSTRNHQQQQQQQQPAQQQQQQQRVTQRNNHRNHHRRRHLA 1072
            |.|..|...|        .|::.:.||..|..|.....|......|..|..:|
Mouse   707 STADFLDQVT--------SQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIA 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	3/19 (16%)
		C2H2 Zn finger	562..582	CDD:275368	4/19 (21%)
		C2H2 Zn finger	594..614	CDD:275368	4/19 (21%)
		C2H2 Zn finger	622..642	CDD:275368	3/19 (16%)
		zf-C2H2	648..670	CDD:278523	9/21 (43%)
		C2H2 Zn finger	650..670	CDD:275368	9/19 (47%)
		zf-H2C2_2	662..684	CDD:290200	8/21 (38%)
		C2H2 Zn finger	678..698	CDD:275368	3/19 (16%)
Zfp148	XP_006522161.1	zf-C2H2	177..199	CDD:333835	4/21 (19%)
		C2H2 Zn finger	179..199	CDD:275368	4/19 (21%)
		zf-H2C2_2	191..216	CDD:372612	7/28 (25%)
		C2H2 Zn finger	207..227	CDD:275368	7/47 (15%)
		zf-H2C2_2	220..244	CDD:372612	11/23 (48%)
		C2H2 Zn finger	235..255	CDD:275368	9/19 (47%)
		zf-H2C2_2	247..272	CDD:372612	8/24 (33%)
		C2H2 Zn finger	263..281	CDD:275368	3/17 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000