DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32767 and Zfp628

DIOPT Version :9

Sequence 1:	NP_001162674.1	Gene:	CG32767 / 31430	FlyBaseID:	FBgn0052767	Length:	1281	Species:	Drosophila melanogaster
Sequence 2:	XP_006228365.1	Gene:	Zfp628 / 100359484	RGDID:	2323809	Length:	1039	Species:	Rattus norvegicus

Alignment Length:	656	Identity:	139/656 - (21%)
Similarity:	230/656 - (35%)	Gaps:	149/656 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   460 QLQQQQQQQQTHPVKHSASG---------SSSTNNNSTTNSTNSNNNTPAATATVTTSYQCVECV 515
            ||......||.| |:.:|:|         ..:........:|.:....|.|..:....|:|.||.
  Rat   390 QLASLLAHQQCH-VEEAAAGRPPPQAEVAEVTCPQEPVAPATPAPPPPPPAPVSAERPYKCAECG 453

  Fly   516 EKFDSKELFDIHRSGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRVVRFRPNFIKHMR 580
            :.|........|...|...                       :||:|..||:..:.......|.|
  Rat   454 KAFKGSSGLRYHLRDHTGE-----------------------RPYQCGECGKAFKRSSLLAIHQR 495

  Fly   581 VHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALASLRGHSKLHSGV 645
            ||||.::    :.|..|...|....:::.|.::|:......|..|||.|...:.||.|..:|:|.
  Rat   496 VHTGLRA----FTCGQCGLTFKWSSHYQYHLRLHSGERPYACTECGKAFRNTSCLRRHRHVHTGE 556

  Fly   646 KLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKICKKKLHTQSSLQTHMQVHLRDQPGAAAAAA 710
            :.|.|.||||.|.|..||:.|.|.|||:.||.|.:|.|.....|:|..|.:.|..::|    .|.
  Rat   557 RPHSCSVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERP----FAC 617

  Fly   711 TAAGAASSKASNSSNSSNSSNSSSSNSSSNGVSAA------VSAATT------------TTTIVK 757
            ...|.....|:.......:...:::.|.:.|.:.|      ::||.|            ...|:.
  Rat   618 PICGRGFVMAAYLQRHLRTHTPATTTSGTTGPAVASQPPTPLAAAPTPLAAQDVHVLPNLQAILS 682

  Fly   758 LE---------PPHEIERPGTSSNQQLQQSQHHQ----------------------MELDDQSGL 791
            ||         ||..: .|.:.:...:|.:|..|                      :......|:
  Rat   683 LEVAGGTAQATPPGPV-APSSQTFLLVQTAQGLQLIPSSVQPPTPPPPPPPPKLILLPPASAGGM 746

  Fly   792 S-----------GDEEDGSG-------GGMNSSSHIVNATTNRLTTGEDSSESSNASLHLNQHSS 838
            .           |....|:|       ||:.     |....|..|:|      ...||.:.|  :
  Rat   747 GNGAARPGPRAVGKAGQGTGVVWFPGPGGLG-----VQGGGNAGTSG------GGQSLIVLQ--N 798

  Fly   839 TSSSPASQHQVSSHQQHVHQQQQQQQQSQQQYLVSAPTRTIVIKNYMQQGSQQQQQQQQQQQHTS 903
            ..|......:||.     .|.|..|:.:..|...:....|:.::...:..:.|.|....|..::|
  Rat   799 VGSGETGPQEVSG-----VQLQPAQEVATVQLQPAQEVTTVQLQPAQEVTTVQLQPLTGQVSNSS 858

  Fly   904 D---PTPVLHAQVIQSGAG----TSNGSGNTSSTNSSSNSSTNIVTTNAGGNLSNGSQLIRKTPI 961
            .   .|...:..|:||||.    ||:|.|....:.:|:....:::......:....|.|:
  Rat   859 GGAVATEAPNLLVVQSGAAEELLTSSGPGEVGDSEASAGMVQDVLFETLQTDEGLQSVLV----- 918

  Fly   962 IHHSTGSSNGSGGSALTSVVQQTGVISPAQSPSSSSTSCSSSTVLVSKATGVPLSIASSAAAALG 1026
                   .:|:.|......||:...:||..:..:::.......::...|....|..:||.|   |
  Rat   919 -------LSGADGEQTRLCVQEVETLSPGLTEPAATDPSGQKLLIFRSAPAADLLESSSVA---G 973

  Fly  1027 GSTIIR 1032
            |:|.::
  Rat   974 GTTTLQ 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32767	NP_001162674.1	C2H2 Zn finger	537..557	CDD:275368	0/19 (0%)
		C2H2 Zn finger	562..582	CDD:275368	5/19 (26%)
		C2H2 Zn finger	594..614	CDD:275368	4/19 (21%)
		C2H2 Zn finger	622..642	CDD:275368	8/19 (42%)
		zf-C2H2	648..670	CDD:278523	12/21 (57%)
		C2H2 Zn finger	650..670	CDD:275368	11/19 (58%)
		zf-H2C2_2	662..684	CDD:290200	11/21 (52%)
		C2H2 Zn finger	678..698	CDD:275368	6/19 (32%)
Zfp628	XP_006228365.1	COG5048	<23..221	CDD:227381
		C2H2 Zn finger	36..56	CDD:275368
		zf-H2C2_2	49..72	CDD:290200
		C2H2 Zn finger	64..84	CDD:275368
		zf-H2C2_2	76..101	CDD:290200
		C2H2 Zn finger	92..112	CDD:275368
		C2H2 Zn finger	120..140	CDD:275368
		zf-H2C2_2	132..157	CDD:290200
		C2H2 Zn finger	148..168	CDD:275368
		zf-H2C2_2	160..185	CDD:290200
		C2H2 Zn finger	176..196	CDD:275368
		zf-H2C2_2	188..213	CDD:290200
		C2H2 Zn finger	204..224	CDD:275368
		C2H2 Zn finger	354..371	CDD:275370
		C2H2 Zn finger	381..401	CDD:275368	4/10 (40%)
		COG5048	<446..635	CDD:227381	61/219 (28%)
		C2H2 Zn finger	449..469	CDD:275368	5/19 (26%)
		zf-H2C2_2	462..486	CDD:290200	7/46 (15%)
		C2H2 Zn finger	477..497	CDD:275368	5/19 (26%)
		C2H2 Zn finger	505..525	CDD:275368	4/19 (21%)
		zf-H2C2_2	517..542	CDD:290200	7/24 (29%)
		C2H2 Zn finger	533..553	CDD:275368	8/19 (42%)
		zf-H2C2_2	546..570	CDD:290200	12/23 (52%)
		C2H2 Zn finger	561..581	CDD:275368	11/19 (58%)
		zf-H2C2_2	573..598	CDD:290200	12/24 (50%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
		zf-H2C2_2	601..625	CDD:290200	6/27 (22%)
		zf-C2H2	615..637	CDD:278523	3/21 (14%)
		C2H2 Zn finger	617..637	CDD:275368	2/19 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100